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抑制剂激活剂等> 免疫与炎症> NF-κB Signaling
PDTC (NF-κB抑制剂/抗氧化剂)
产品编号: S1808
产品包装:1g
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1g 5g
价格: ¥ 145.00
产品简介
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产品编号 产品名称 产品包装 产品价格
S1808 PDTC (NF-κB抑制剂/抗氧化剂) 1g 145.00元
S1809 PDTC (NF-κB抑制剂/抗氧化剂) 5g 366.00元

PDTC的全称为Ammonium pyrrolidinedithiocarbamate或Pyrrolidinedithiocarbamic acid,ammonium salt,是一种可
以通透细胞膜的NF-κB活化(NF-κB activation)抑制剂,可以在多种细胞中抑制NF-κB的激活。PDTC也是一种抗氧化剂(antioxidant),也是一种金属离子螯合剂(metal chelator),并且可以在酸性溶液中沉淀As,Bi,Cd,Co,Cu,Fe,Mn,Ni,Pb,Sb,Sn,V,Zn等重金属。PDTC可以诱导大鼠平滑肌细胞发生凋亡,也可以抑制白血病细胞HL-60发生凋亡。
PDTC分子量为164.29,分子式为C5H9NS2·NH3,CAS Number:5108-96-3。本产品为进口分装,纯度大于99%。
PDTC可溶于水(1mg/ml),在DMSO中的溶解度可达到100mM。
包装清单:

产品编号 产品名称 包装
S1808 PDTC(NF-κB抑制剂/抗氧化剂) 1g
说明书 1份

保存条件:
4℃保存。配制成母液后-20℃可保存3个月。
注意事项:
本产品对人体有刺激性,操作时请小心,并注意适当防护以避免直接接触人体或吸入体内。
本产品仅限于专业人员的科学研究用,不得用于临床诊断或治疗,不得用于食品或药品,不得存放于普通住宅内。
为了您的安全和健康,请穿实验服并戴一次性手套操作。

使用说明:
1. PDTC常见使用浓度范围为10-100μM。具体的最佳工作浓度请参考相关文献,或根据实验目的,以及所培养的特定细胞和组织,通过实验进行摸索和优化。
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