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JC-1
产品编号: C2005
产品包装: 1mg
产品价格: 791.00元
产品简介
使用说明
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产品编号 产品名称 产品包装 产品价格
C2005 JC-1 1mg 791.00元

      JC-1也称CBIC2(3)或5,5′,6,6′-Tetrachloro-1,1′,3,3′-tetraethyl-imidacarbocyanine iodide,分子式为C25H27Cl4IN4,分子量为652.23,CAS Number 3520-43-2,纯度>95%。
      JC-1是一种广泛用于检测线粒体膜电位(mitochondrial membrane potential)△Ψm 的理想荧光探针。可以检测细胞、组织或纯化的线粒体膜电位。在线粒体膜电位较高时,JC-1聚集在线粒体的基质(matrix)中,形成聚合物(J-aggregates),可以产生红色荧光;在线粒体膜电位较低时,JC-1不能聚集在线粒体的基质中,此时JC-1为单体(monomer),可以产生绿色荧光。这样就可以非常方便地通过荧光颜色的转变来检测线粒体膜电位的变化。常用红绿荧光的相对比例来衡量线粒体去极化的比例。
      线粒体膜电位的下降是细胞凋亡早期的一个标志性事件。通过JC-1从红色荧光到绿色荧光的转变可以很容易地检测到细胞膜电位的下降,同时也可以用JC-1从红色荧光到绿色荧光的转变作为细胞凋亡早期的一个检测指标。
      JC-1单体的最大激发波长为514nm,最大发射波长为529nm;JC-1聚合物(J-aggregates)的最大激发波长为585nm,最大发射波长为590nm。实际观察时,使用常规的观察红色荧光和绿色荧光的设置即可。
      JC-1稀释和使用时有一些特殊的要求,因此对于初次使用JC-1的用户或对于JC-1的使用不是非常熟悉的用户,我们建议使用碧云天的线粒体膜电位检测试剂盒(JC-1)(C2006),该试剂盒配套提供了一些相关试剂,使用起来更加便捷。
      本JC-1溶解在DMSO中,浓度为5mg/ml,共200μl。
包装清单:

产品编号 产品名称 包装
C2005 JC-1(5mg/ml) 50μl/管,共4管
说明书 1份

保存条件:
      -20℃避光保存。
注意事项:
      JC-1如果一次使用量较小,需把每管再适当进行分装,尽量避免反复冻融。
      JC-1在4℃、冰浴等较低温度情况下会凝固而粘在离心管管底、管壁或管盖内,可以20-25℃水浴温育片刻至全部融解后使用。
      本产品仅限于专业人员的科学研究用,不得用于临床诊断或治疗,不得用于食品或药品,不得存放于普通住宅内。
      为了您的安全和健康,请穿实验服并戴一次性手套操作。

使用说明:
JC-1用于检测细胞的线粒体膜电位时常用的浓度范围为1-20μg/ml,对于很多细胞适宜采用的JC-1浓度为10μg/ml。详细的使用方法请参考相关文献资料。
相关产品请点击如下按钮:

使用本产品的文献:
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Isoorientin induces apoptosis through mitochondrial dysfunction and inhibition of PI3K/Akt signaling pathway inHepG2 cancer cells.
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Niacin protects against UVB radiation-induced apoptosis in cultured human skin keratinocytes.
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Dioscin, a natural steroid saponin, shows remarkable protective effect against acetaminophen-induced liverdamage in vitro and in vivo.
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87.Yu H, Li X, Sun S, Gao X, Zhou D.
c-Met inhibitor SU11274 enhances the response of the prostate cancer cell line DU145 to ionizing radiation.
Biochem Biophys Res Commun. 2012 Oct 26;427(3):659-65. 
88.Liu Q, Yao JY, Qian C, Chen R, Li XY, Liu SW, Sun BG, Song LS, Hong J.
Effects of propofol on ischemia-induced ventricular arrhythmias and mitochondrial ATP-sensitive potassium channels.
Acta Pharmacol Sin. 2012 Dec;33(12):1495-501.
89.Chen XM, Liu J, Wang T, Shang J.
Colchicine-induced apoptosis in human normal liver L-02 cells by mitochondrial mediated pathways.
Toxicol In Vitro.2012 Aug;26(5):649-55.
90.Zhu X, Chen C, Ye D, Guan D, Ye L, Jin J, Zhao H, Chen Y, Wang Z, Wang X, Xu Y.
Diammonium glycyrrhizinate upregulates PGC-1α and protects against Aβ1-42-induced neurotoxicity.
PLoS One. 2012;7(4):e35823.
91.Zhang W, Huang Q, Hua Z.
Galangin and TRAIL cooperate to suppress A549 lung cancer proliferation via apoptosis and p38 MAPK activation.
Acta Pharmaceutica Sinica B. 2012 Dec;2(6):569-74.
92.Wang CQ, Zhang J, Sun YF, Wang D, Li CJ, Li WH, Lu C, Liu Z, Wu H, Hou XF, Chen C, Zhou X.
Detection of Neurotrophin-4 (NT-4) in Ejaculated Bull Spermatozoa and its Effect on SpermatozoaMitochondrial Activity.
Reprod Domest Anim.  2013 Feb;48(1):131-6.
93.Wei Z, Yuan S, Hao J, Fang X.
Mechanism of inhibition of P-glycoprotein mediated efflux by Pluronic P123/F127 block copolymers: Relationship between copolymer concentration and inhibitory activity.
Eur J Pharm Biopharm. 2013 Feb;83(2):266-73.
94.Mao Z, Xia W, Wang J, Chen T, Zeng Q, Xu B, Li W, Chen X, Xu S.
Perfluorooctane sulfonate induces apoptosis in lung cancer A549 cells through reactive oxygen species-mediated mitochondrion-dependent pathway.
J Appl Toxicol. 2013 Nov;33(11):1268-76.
95.Zhang L, Sang H, Liu Y, Li J.
Manganese activates caspase-9-dependent apoptosis in human bronchial epithelial cells.
Hum Exp Toxicol. 2013 Nov;32(11):1155-63.
96.Shi CM, Xu GF, Yang L, Fu ZY, Chen L, Fu HL, Shen YH, Zhu L, Ji CB, Guo XR.
Overexpression of TFAM Protects 3T3-L1 Adipocytes from NYGGF4 (PID1) Overexpression-Induced InsulinResistance and Mitochondrial Dysfunction.
Cell Biochem Biophys. 2013 Jul;66(3):489-97.
97.Zhang X, Xie P, Zhang X, Zhou W, Zhao S, Zhao Y, Cai Y.
Toxic effects of microcystin-LR on the HepG2 cell line under hypoxic and normoxic conditions.
J Appl Toxicol. 2013 Oct;33(10):1180-6.
98.Hu Y, Qi Y, Liu H, Fan G, Chai Y.
Effects of celastrol on human cervical cancer cells as revealed by ion-trap gas chromatography-massspectrometry based metabolic profiling.
Biochim Biophys Acta. 2013 Mar;1830(3):2779-89.
99.Guo D, Bi H, Liu B, Wu Q, Wang D, Cui Y.
Reactive oxygen species-induced cytotoxic effects of zinc oxide nanoparticles in rat retinal ganglion cells.
Toxicol In Vitro.2013 Mar;27(2):731-8.
100.Yue B, Zhang YS, Xu HM, Zhao CR, Li YY, Qin YZ, Wang RQ, Sun D, Yuan Y, Lou HX, Qu XJ.
Riccardin D-26, a synthesized macrocyclic bisbibenzyl compound, inhibits human hepatocellular carcinoma growth through induction of apoptosis in p53-dependent way.
Cancer Lett. 2013 Jan 1;328(1):104-13.
101.Wang F, Gao Q, Guo S, Cheng J, Sun X, Li Q, Wang T, Zhang Z, Cao W, Tian Y.
The sonodynamic effect of curcumin on THP-1 cell-derived macrophages.
Biomed Res Int. 2013;2013:737264.
102.Pi J, Jin H, Liu R, Song B, Wu Q, Liu L, Jiang J, Yang F, Cai H, Cai J.
Pathway of cytotoxicity induced by folic acid modified selenium nanoparticles in MCF-7 cells.
Appl Microbiol Biotechnol. 2013 Feb;97(3):1051-62.
103.Song S, Wang S, Ma J, Yao L, Xing H, Zhang L, Liao L, Zhu D.
Biliverdin reductase/bilirubin mediates the anti-apoptotic effect of hypoxia in pulmonary arterial smooth musclecells through ERK1/2 pathway.
Exp Cell Res.2013 Aug 1;319(13):1973-87.
104.Yang Y, Yan X, Duan W, Yan J, Yi W, Liang Z, Wang N, Li Y, Chen W, Yu S, Jin Z, Yi D.
Pterostilbene Exerts Antitumor Activity via the Notch1 Signaling Pathway in Human Lung Adenocarcinoma Cells.
PLoS One. 2013 May 3;8(5):e62652.
105.Liang D, Xiang L, Yang M, Zhang X, Guo B, Chen Y, Yang L, Cao J.
ZnT7 can protect MC3T3-E1 cells from oxidative stress-induced apoptosis via PI3K/Akt and MAPK/ERK signalingpathways.
Cell Signal. 2013 May;25(5):1126-35.
106.Fan Y, Wang C, Zhang Y, Hang P, Liu Y, Pan Z, Wang N, Du Z.
Genistein ameliorates adverse cardiac effects induced by arsenic trioxide through preventing cardiomyocytesapoptosis.
Cell Physiol Biochem. 2013;31(1):80-91.
107.Sun S, Pan S, Miao A, Ling C, Pang S, Tang J, Chen D, Zhao C.
Active extracts of black tea (Camellia Sinensis) induce apoptosis of PC-3 prostate cancer cells via mitochondrialdysfunction.
Oncol Rep. 2013 Aug;30(2):763-72.
108.Li P, Xue Y, Zhang W, Teng F, Sun Y, Qu T, Chen X, Cheng X, Song B, Luo W, Yu Q.
Sodium fluoride induces apoptosis in odontoblasts via a JNK-dependent mechanism.
Toxicology. 2013 Jun 7;308:138-45.
109.Liu Y, Wang L, Wu Y, Lv C, Li X, Cao X, Yang M, Feng D, Luo Z.
Pterostilbene exerts antitumor activity against human osteosarcoma cells by inhibiting the JAK2/STAT3 signalingpathway.
Toxicology. 2013 Feb 8;304:120-31.
110.Tang Q, Li G, Wei X, Zhang J, Chiu JF, Hasenmayer D, Zhang D, Zhang H.
Resveratrol-induced apoptosis is enhanced by inhibition of autophagy in esophageal squamous cell carcinoma.
Cancer Lett.2013 Aug 19;336(2):325-37.
111.Chen Y, Zhuang X, Xu Z, Lu L, Guo H, Wu W, Liao X.
Higenamine Combined with [6]-Gingerol Suppresses Doxorubicin-Triggered Oxidative Stress and Apoptosis in Cardiomyocytes via Upregulation of PI3K/Akt Pathway.
Evidence-Based Complementary and Alternative Medicine.2013;2013:970490.
112.Ma J, Zhang L, Zhang J, Liu M, Wei L, Shen T, Ma C, Wang Y, Chen Y, Zhu D.
15-lipoxygenase-1/15-hydroxyeicosatetraenoic acid promotes hepatocellular cancer cells growth through protein kinase B and heat shock protein 90 complex activation.
Int J Biochem Cell Biol. 2013 Jun;45(6):1031-41.
113.Cai B, Li X, Wang Y, Liu Y, Yang F, Chen H, Yin K, Tan X, Zhu J, Pan Z, Wang B, Lu Y.
Apoptosis of bone marrow mesenchymal stem cells caused by homocysteine via activating JNK signal.
PLoS One. 2013 May 7;8(5):e63561.
114.Wu C, Wang C, Han T, Zhou X, Guo S, Zhang J.
Insight into the Cellular Internalization and Cytotoxicity of Graphene Quantum Dots.
Adv Healthc Mater. 2013 Dec;2(12):1613-9.
115.Ma LS, Jiang CY, Cui M, Lu R, Liu SS, Zheng BB, Li L, Li X.
Fluopsin C induces oncosis of human breast adenocarcinoma cells.
Acta Pharmacol Sin.2013 Aug;34(8):1093-100.
116.Sun L, Zhao M, Yu XJ, Wang H, He X, Liu JK, Zang WJ.
Cardioprotection by acetylcholine: a novel mechanism via mitochondrial biogenesis and function involving the PGC-1α pathway.
J Cell Physiol. 2013 Jun;228(6):1238-48.
117.Yuan F, Dong P, Wang X, Fu X, Dai M, Zhang W.
Toxicological effects of cigarette smoke on Ana-1 macrophages in vitro.
Exp Toxicol Pathol.2013 Nov;65(7-8):1011-8.
118.Li T, Liu Z, Jiang K, Ruan Q.
Angiopoietin2 enhances doxorubin resistance in HepG2 cells by upregulating survivin and Ref-1 via MSK1activation.
Cancer Lett.2013 Sep 1;337(2):276-84.
119.Wu WY, Wang WY, Ma YL, Yan H, Wang XB, Qin YL, Su M, Chen T, Wang YP.
Sodium tanshinone IIA silate inhibits oxygen-glucose deprivation/recovery-induced cardiomyocyte apoptosis viasuppression of the NF-κB/TNF-α pathway.
Br J Pharmacol. 2013 Jul;169(5):1058-71.
120.Zheng J, Zhang Y, Xu W, Luo Y, Hao J, Shen XL, Yang X, Li X, Huang K.
Zinc protects HepG2 cells against the oxidative damage and DNA damage induced by ochratoxin A.
Toxicol Appl Pharmacol. 2013 Apr 15;268(2):123-31.
121.E Q, Liu X, Liu Y, Liu W, Zuo J.
Over-expression of GRP75 inhibits liver injury induced by oxidative damage.
Acta Biochim Biophys Sin (Shanghai). 2013 Feb;45(2):129-34.
122.Yi F, He X, Wang D.
Lycopene Protects Against MPP+-Induced Cytotoxicity by Maintaining Mitochondrial Function in SH-SY5Y Cells.
Neurochem Res. 2013 Aug;38(8):1747-57.
123.Guo R, Liu B, Zhou S, Zhang B, Xu Y.
The protective effect of fasudil on the structure and function of cardiac mitochondria from rats with type 2 diabetes induced by streptozotocin with a high-fat diet is mediated by the attenuation of oxidative stress.
Biomed Res Int. 2013;2013:430791.
124.Li JW, Ning N, Ma YZ, Zhang R, Tan F, Chen NH.
Claulansine F suppresses apoptosis induced by sodium nitroprusside in PC12 cells.
Free Radic Res. 2013 Jul;47(6-7):488-97.
125.Wang Q,X Cheng X,Zhang D, Gao X, Zhou L, Qin X, Xie G, Liu K, Qin Y, Liu B, Qin M.
Tectorigenin Attenuates Palmitate-Induced Endothelial Insulin Resistance via Targeting ROS-Associated Inflammation and IRS-1 Pathway.
PLOS ONE.2013 Jun 19;8(6):e66417.
126.Jiang L, Liu Y, Ma MM, Tang YB, Zhou JG, Guan YY.
Mitochondria dependent pathway is involved in the protective effect of bestrophin-3 on hydrogen peroxide-induced apoptosis in basilar artery smooth muscle cells.
Apoptosis. 2013 May;18(5):556-65.
127.Huang H, Wu K, You Q, Huang R, Li S, Wu K.
Naringin inhibits high glucose-induced cardiomyocyte apoptosis by attenuating mitochondrial dysfunction andmodulating the activation of the p38 signaling pathway.
Int J Mol Med. 2013 Aug;32(2):396-402.
128.Zhou D, Wei A, Cao C, Ruan J.
DICO, a novel nonaromatic B-ring flavonoid, induces G2/M cell cycle arrest and apoptosis in human hepatomacells.
Food Chem Toxicol.2013 Jul;57:322-9.
129.Luo CL, Chen XP, Li LL, Li QQ, Li BX, Xue AM, Xu HF, Dai DK, Shen YW, Tao LY, Zhao ZQ.
Poloxamer 188 attenuates in vitro traumatic brain injury-induced mitochondrial and lysosomal membranepermeabilization damage in cultured primary neurons.
J Neurotrauma. 2013 Apr 1;30(7):597-607.
130.Li X, Tao H, Xie K, Ni Z, Yan Y, Wei K, Chuang PY, He JC, Gu L.
cAMP signaling prevents podocyte apoptosis via activation of protein kinase A and mitochondrial fusion.
PLoS One. 2014 Mar 18;9(3):e92003.
131.Sun J, Bai S, Bai W, Zou F, Zhang L, Li G, Hu Y, Li M, Yan R, Su Z, Huang Y.
1,3-Dichloro-2-propanol inhibits progesterone production through the expression of steroidogenic enzymes and cAMP concentration in Leydig cells.
Food Chem. 2014 Jul 1;154:330-6.
132.Chang C, Wu G, Gao P, Yang L, Liu W, Zuo J.
Upregulated Parkin expression protects mitochondrial homeostasis in DJ-1 konckdown cells and cells overexpressing the DJ-1 L166P mutation.
Mol Cell Biochem. 2014 Feb;387(1-2):187-95.
133.Yang L, Di G, Qi X, Qu M, Wang Y, Duan H, Danielson P, Xie L, Zhou Q.
Substance P promotes diabetic corneal epithelial wound healing through molecular mechanisms mediated via the neurokinin-1 receptor.
Diabetes.2014 Dec;63(12):4262-74.
134.Li D, Ye Y, Lin S, Deng L, Fan X, Zhang Y, Deng X, Li Y, Yan H, Ma Y.
Evaluation of deoxynivalenol-induced toxic effects on DF-1 cells in vitro: cell-cycle arrest, oxidative stress, and apoptosis.
Environ Toxicol Pharmacol. 2014 Jan;37(1):141-9.
135.He M, Dong C, Xie Y, Li J, Yuan D, Bai Y, Shao C.
Reciprocal bystander effect between α-irradiated macrophage and hepatocyte is mediated by cAMP through a membrane signaling pathway.
Mutat Res Fundam Mol Mech Mutagen. 2014 Mar 20;763-764C:1-9.
136.Tang C, Liang J, Qian J, Jin L, Du M, Li M, Li D.
Opposing role of JNK-p38 kinase and ERK1/2 in hydrogen peroxide-induced oxidative damage of human trophoblast-like JEG-3 cells.
Int J Clin Exp Pathol. 2014 Feb 15;7(3):959-68.
137.Chu JH, Zhao CR, Song ZY, Wang RQ, Qin YZ, Li WB, Qu XJ.
1082-39, an analogue of sorafenib, inhibited human cancer cell growth more potently than sorafenib.
Biomed Pharmacother. 2014 Apr;68(3):335-41.
138.Pan H, Cheng L, Yang H, Zou W, Cheng R, Hu T.
Lysophosphatidic acid rescues human dental pulp cells from ischemia-induced apoptosis.
J Endod. 2014 Feb;40(2):217-22. 
139.Zheng L, Sun X, Zhu X, Lv F, Zhong Z, Zhang F, Guo W, Cao W, Yang L, Tian Y.
Apoptosis of THP-1 derived macrophages induced by sonodynamic therapy using a new sonosensitizer hydroxyl acetylated curcumin.
PLoS One. 2014 Mar 27;9(3):e93133.
140.Cui SX, Zhang HL, Xu WF, Qu XJ.
13F-1, a novel 5-fluorouracil prodrug containing an Asn-Gly-Arg (NO2) COOCH3 tripeptide, inhibits human colonic carcinoma growth by targeting Aminopeptidase N (APN/CD13).
Eur J Pharmacol. 2014 Jul 5;734:50-9.
141.Fang L, Bai C, Chen Y, Dai J, Xiang Y, Ji X, Huang C, Dong Q.
Inhibition of ROS production through mitochondria-targeted antioxidant and mitochondrial uncoupling increases post-thaw sperm viability in yellow catfish.
Cryobiology.2014 Dec;69(3):386-93.
142.Wang C, Xia W, Jiang Q, Xu Y, Yu P.
Differential effects of lipid fractions from silver carp brain on human cervical carcinoma cells in vitro.
Food Funct. 2014 Sep;5(9):2194-201.
143.Fan S, Li X, Lin J, Chen S, Shan J, Qi G.
Honokiol inhibits tumor necrosis factor-α-stimulated rat aortic smooth muscle cell proliferation via caspase- and mitochondrial-dependent apoptosis.
Inflammation. 2014 Feb;37(1):17-26.
144.Guo P, Pi H, Xu S, Zhang L, Li Y, Li M, Cao Z, Tian L, Xie J, Li R, He M, Lu Y, Liu C, Duan W, Yu Z, Zhou Z.
Melatonin Improves Mitochondrial Function by Promoting MT1/SIRT1/PGC-1 Alpha-Dependent Mitochondrial Biogenesis in Cadmium-Induced Hepatotoxicity In Vitro.
Toxicol Sci. 2014;142(1):182-95.
145.Li D, Ma H, Ye Y, Ji C, Tang X, Ouyang D, Chen J, Li Y, Ma Y.
Deoxynivalenol induces apoptosis in mouse thymic epithelial cells through mitochondria-mediated pathway.
Environ Toxicol Pharmacol. 2014 Jul;38(1):163-71.
146.Liu L, Li T, Tan J, Fu J, Guo Q, Ji H, Zhang Y.
NG as a novel nitric oxide donor induces apoptosis by increasing reactive oxygen species and inhibiting mitochondrial function in MGC803 cells.
Int Immunopharmacol. 2014 Aug 16;23(1):27-36.
147.Zhang X, Yu Q, Jiang W, Bi Y, Zhang Y, Gong M, Wei X, Li T, Chen J.
All-trans retinoic acid suppresses apoptosis in PC12 cells injured by oxygen and glucose deprivation via the retinoic acid receptor α signaling pathway.
Mol Med Rep. 2014 Nov;10(5):2549-55.
148.Jiang L, Zhao MN, Liu TY, Wu XS, Weng H, Ding Q, Shu YJ, Bao RF, Li ML, Mu JS, Wu WG, Ding QC, Cao Y, Hu YP, Shen BY, Tan ZJ, Liu YB.
Bufalin induces cell cycle arrest and apoptosis in gallbladder carcinoma cells.
Tumour Biol. 2014 Nov;35(11):10931-41.
149.Sun ZB, Wang JW, Xiao H, Zhang QS, Kan WS, Mo FB, Hu S, Ye SN.
Icariin may benefit the mesenchymal stem cells of patients with steroid-associated osteonecrosis by ABCB1-promoter demethylation: a preliminary study.
Osteoporos Int.2015 Jan;26(1):187-97.
150.Pan HY, Yang H, Shao MY, Xu J, Zhang P, Cheng R, Hu T.
Sphingosine-1-phosphate mediates AKT/ERK maintenance of dental pulp homoeostasis.
Int Endod J. 2015;48(5):460-468.
151.Liu Y, Jiao R, Ma ZG, Liu W, Wu QQ, Yang Z, Li FF, Yuan Y, Bian ZY, Tang QZ.
Sanguinarine inhibits angiotensin II-induced apoptosis in H9c2 cardiac cells via restoring reactive oxygen species-mediated decreases in the mitochondrial embrane potential.
Mol Med Rep.2015 Sep;12(3):3400-8.
152.Duan C, Zhang B, Deng C, Cao Y, Zhou F, Wu L, Chen M, Shen S, Xu G, Zhang S, Duan G, Yan H, Zou X.
Piperlongumine induces gastric cancer cell apoptosis and G2/M cell cycle arrest both in vitro and in vivo.
Tumour Biol. 2016 Aug;37(8):10793-804.
153.Wang L, Qin W, Zhang J, Bao C, Zhang H, Che Y, Sun C, Gu J, Feng X, Du C, Han W, Richard PL, Lei L.
Adh enhances Actinobacillus pleuropneumoniae pathogenicity by binding to OR5M11 and activating p38which induces apoptosis of PAMs and IL-8 release.
Sci Rep. 2016 Apr 5;6:24058.
154.Li Y, Sun Y, Jing L, Wang J, Yan Y, Feng Y, Zhang Y, Liu Z, Ma L, Diao A.
Lysosome Inhibitors Enhance the Chemotherapeutic Activity of Doxorubicin in HepG2 Cells.
Chemotherapy. 2017;62(2):85-93.
155.Zhao J, Qi X, Dai Q, He X, Dweep H, Guo M, Luo Y, Gretz N, Luo H, Huang K, Xu W.
Toxicity study of ochratoxin Ausing HEK293 and HepG2 cell lines based on microRNA profiling.
Hum Exp Toxicol. 2016 Feb 18. pii: 0960327116632048. [Epub ahead of print]
156.Liu H, Peng H, Chen S, Liu Y, Xiang H, Chen R, Chen W, Zhao S, Chen P, Lu H.
S1PR2 antagonist protects endothelial cells against high glucose-induced mitochondrialapoptosis through the Akt/GSK-3β signaling pathway.
Biochem Biophys Res Commun. 2017 Aug 26;490(3):1119-1124.
157.Yaoi X, Lu B, Lü C, Bai Q, Yan D, Xu H.
Taraxerol Induces Cell Apoptosis through A Mitochondria-Mediated Pathway in HeLa Cells.
Cell J. 2017 Oct;19(3):512-519.
158.Guo X, Zhang G, Chen L, Khan AA, Gu B, Li B.
Newborn Neurons Are Damaged In Vitro by a Low Concentration of Silver Nanoparticles Through the Inflammatory Oxidative Stress Pathway.
DNA Cell Biol. 2017 Dec;36(12):1062-1070.
159.Guo Q.
Changes in mitochondrial function during EMT induced by TGFβ-1 in pancreatic cancer.
Oncol Lett. 2017 Mar;13(3):1575-1580.
160.Wu H, Liu S, Gong J, Liu J, Zhang Q, Leng X, Zhang N, Li Y.
VCPA,a novel synthetic derivative ofα-tocopheryl succinate, sensitizes human gastric cancer to doxorubicin-induced apoptosis via ROS-dependent mitochondrial dysfunction.
Cancer Lett. 2017 May 1;393:22-32.
161.Wang T, Hou J, Su C, Zhao L, Shi Y.
Hyaluronic acid-coated chitosan nanoparticles induce ROS-mediated tumor cell apoptosis and enhance antitumor efficiency by targeted drug delivery via CD44.
J Nanobiotechnology. 2017 Jan 10;15(1):7.
162.He Z, Pu L, Yuan C, Jia M, Wang J.
Nutrition deficiency promotes apoptosis of cartilage endplate stem cells ina caspase-independent manner partially through upregulating BNIP3.
Acta Biochim Biophys Sin (Shanghai). 2017 Jan;49(1):25-32.
163.Zhang B, Xu L, Zhuo N, Shen J.
Resveratrol protects against mitochondrial dysfunction through autophagy activation in humannucleus pulposus cells.
Biochem Biophys Res Commun. 2017 Nov 4;493(1):373-381.
164.Chen H, Tang X, Zhou B, Zhou Z, Xu N, Wang Y.
A ROS-mediated mitochondrial pathway and Nrf2 pathway activation are involved in BDE-47induced apoptosis in Neuro-2a cells.
Chemosphere. 2017 Oct;184:679-686.
165.Hong S, Hong L, Li B, Wu D, Liu C, Min J, Guo W, Hu M, Tang J, Li Y.
The role of GPX1 inthe pathogenesis of female pelvic organ prolapse.
PLoS One. 2017 Aug 7;12(8):e0181896.
166.Zhang J, Cai Q, Jiang M, Liu Y, Gu H, Guo J, Sun H, Fang J, Jin L.
Mesencephalic astrocyte-derived neurotrophic factor alleviated 6-OHDA-induced cell damage viaROS-AMPK/mTOR mediated autophagic inhibition.
Exp Gerontol. 2017 Mar;89:45-56.
167.Wen L, Jiang X, Sun J, Li X, Li X, Tian L, Li Y, Bai W.
Cyanidin-3-O-glucoside promotes the biosynthesis of progesterone throughthe protection of mitochondrial function in Pb-exposed rat leydig cells.
Food Chem Toxicol. 2017 Oct 10. pii: S0278-6915(17)30586-0.
168.Li R, Zhou P, Guo Y, Lee JS, Zhou B.
Tris (1,3-dichloro-2-propyl) phosphate-induced apoptotic signaling pathways in SH-SY5Yneuroblastoma cells.
Neurotoxicology. 2017 Jan;58:1-10.
169.Yin K, Zhu R, Wang S, Zhao RC.
Low-Level Laser Effect on Proliferation, Migration, and Antiapoptosis of Mesenchymal StemCells.
Stem Cells Dev. 2017 May 15;26(10):762-775.
170.Lei W, Li Q, Su S, Bu J, Huang Q, Li Z.
Chlamydia trachomatis plasmid-encoded protein pORF5 protects mitochondrial function by inducing mitophagy and increasing HMGB1 expression.
Pathog Dis. 2017 Dec 29;75(9).
171.Xie K, Zhu M, Xiang P, Chen X, Kasimumali A, Lu R, Wang Q, Mou S, Ni Z, Gu L, Pang H.
Protein Kinase A/CREB Signaling Prevents Adriamycin-Induced Podocyte Apoptosis viaUpregulation of Mitochondrial Respiratory Chain Complexes.
Mol Cell Biol. 2017 Dec 13;38(1). pii: e00181-17.
172.Ma X, Lin W, Lin Z, Hao M, Gao X, Zhang Y, Kuang H.
Liraglutide alleviates H2O2-induced retinal ganglion cells injury by inhibiting autophagy through mitochondrial pathways.
Peptides. 2017 Jun;92:1-8.
173.Xu X, Luo C, Zhang Z, Hu J, Gao X, Zuo Y, Wang Y, Zhu S.
Mdivi 1 attenuates sodium azide induced apoptosis in H9c2 cardiac muscle cells.
Mol Med Rep. 2017 Nov;16(5):5972-5978.
174.Xu H, Cao H, Zhu G, Liu S, Li H.
Overexpression of microRNA-145 protects against rat myocardial infarction through targetingPDCD4.
Am J Transl Res. 2017 Nov 15;9(11):5003-5011.
175.Dai C, Ciccotosto GD, Cappai R, Wang Y, Tang S, Xiao X, Velkov T.
Minocycline attenuates colistin-induced neurotoxicity via suppression of apoptosis, mitochondrial dysfunction and oxidative stress.
J Antimicrob Chemother. 2017 Jun 1;72(6):1635-1645.
176.Zhang L, Zhou Y, Chen K, Shi P, Li Y, Deng M, Jiang Z, Wang X, Li P, Xu B.
The pan-Bcl2 Inhibitor AT101 Activates the Intrinsic Apoptotic Pathway and Causes DNA Damage in Acute Myeloid Leukemia Stem-Like Cells.
Target Oncol. 2017 Oct;12(5):677-687.
177.Qu X, Sheng J, Shen L, Su J, Xu Y, Xie Q, Wu Y, Zhang X, Sun L.
Autophagy inhibitor chloroquine increases sensitivity to cisplatin in QBC939 cholangiocarcinomacells by mitochondrial ROS.
PLoS One. 2017 Mar 16;12(3):e0173712.
178.Lin C, Zhang M, Zhang Y, Yang K, Hu J, Si R, Zhang G, Gao B, Li X, Xu C, Li C, Hao Q, Guo W.
Helix B surface peptide attenuates diabetic cardiomyopathy via AMPK-dependent autophagy.
Biochem Biophys Res Commun. 2017 Jan 22;482(4):665-671.
179.Yi Li, Qingqin Tang, Peng Wang, Jiahong Qin, Haidong Wu, Jiali Lin, and Zitong Huang.
Dynamic Changes of Mitochondrial Fusion and Fission inBrain Injury after Cardiac Arrest in Rats.
Hindawi BioMed Research International Volume 2017, Article ID 1948070, 9 pages.
180.Chen W, Zhang X, Fan J, Zai W, Luan J, Li Y, Wang S, Chen Q, Wang Y, Liang Y, Ju D.
Tethering Interleukin-22 to Apolipoprotein A-I Ameliorates Mice from Acetaminophen-inducedLiver Injury.
Theranostics. 2017 Sep 26;7(17):4135-4148.
181.Ci X, Zhou J, Lv H, Yu Q, Peng L, Hua S.
Betulin exhibits anti-inflammatory activity in LPS-stimulated macrophages and endotoxin-shocked mice throughan AMPK/AKT/Nrf2-dependent mechanism.
Cell Death Dis. 2017 May 18;8(5):e2798.
182.Li CJ, Jiang YW, Chen SX, Li HJ, Chen L, Liu YT, Gao S, Zhao Y, Zhu XL, Wang HT, Wang FG1, Zheng L, Zhou X.
4-Methylcatechol inhibits cell growth and testosterone production in TM3 Leydig cells by reducing mitochondrial activity.
Andrologia. 2017 Feb;49(1). doi: 10.1111/and.12581. Epub 2016 May 5.
183.Fan W, Han D, Sun Z, Ma S, Gao L, Chen J, Li X, Li X, Fan M, Li C, Hu D, Wang Y, Cao F.
Endothelial deletion of mTORC1 protects against hindlimb ischemia in diabetic mice viaactivation of autophagy, attenuation of oxidative stress and alleviation of inflammation.
Free Radic Biol Med. 2017 Jul;108:725-740.
184.Jiang Q, Liu G, Wang X, Hou Y, Duan Y, Wu G, Yin Y, Yao K.
Mitochondrial pathway is involved inthe protective effects of alpha-ketoglutarate on hydrogenperoxide induced damage to intestinal cells.
Oncotarget. 2017 Aug 24;8(43):74820-74835.
185.Wang X, Guo Q, Tao L, Zhao L, Chen Y, An T, Chen Z, Fu R.
E platinum,a newly synthesized platinum compound, induces apoptosis through ROS-triggeredER stress in gastric carcinoma cells.
Mol Carcinog. 2017 Jan;56(1):218-231.
186.Yang Y, Cheng L, Wang Y, Han Y, Liu J, Deng X, Chao L.
Expression of NDUFA13 in asthenozoospermia and possible pathogenesis.
Reprod Biomed Online. 2017 Jan;34(1):66-74.
187.Yang X, Liu T, Chen B, Wang F, Yang Q, Chen X.
Grape seed proanthocyanidins prevent irradiation-induced differentiation of human lungfibroblasts by ameliorating mitochondrial dysfunction.
Sci Rep. 2017 Mar 3;7(1):62.
188.Guo J, Wang Y, Wang J, Zhang J, Fang J.
Radiosensitization of oral tongue squamous cell carcinoma by nanosecond pulsed electric fields (nsPEFs).
Bioelectrochemistry. 2017 Feb;113:35-41.
189.Feng F, Ren Q, Wu S, Saeed M, Sun C.
Hoxa5 increases mitochondrial apoptosis by inhibiting Akt/mTORC1/S6K1 pathway in mice whiteadipocytes.
Oncotarget. 2017 Aug 24;8(56):95332-95345.
190.Shen J, Xu S, Zhou H, Liu H, Jiang W, Hao J, Hu Z.
IL-1β induces apoptosis and autophagy via mitochondria pathway in human degenerativenucleus pulposus cells.
Sci Rep. 2017 Jan 25;7:41067.
191.Dai J, Wu S, Kong Y, Chi Z, Si L, Sheng X, Cui C, Fang J, Zhang J, Guo J.
Nanosecond Pulsed Electric Fields Enhance the Anti-tumour Effects ofthe mTOR InhibitorEverolimus against Melanoma.
Sci Rep. 2017 Jan 5;7:39597.
192.Sun R, Zhang J, Wei H, Meng X, Ding Q, Sun F, Cao M, Yin L, Pu Y.
Acetyl-l-carnitine partially prevents benzene-induced hematotoxicity and oxidative stress in C3H/He mice.
Environ Toxicol Pharmacol. 2017 Apr;51:108-113.
193.Wang Z, Hou L, Huang L, Guo J, Zhou X.
Exenatide improves liver mitochondrial dysfunction and insulin resistance by reducing oxidativestress in high fat diet-induced obese mice.
Biochem Biophys Res Commun. 2017 Apr 22;486(1):116-123.
194.Jiang Y, Wang X, Hu D1.
Furanodienone induces G0/G1 arrest and causes apoptosis via the ROS/MAPKs-mediatedcaspase-dependent pathway in human colorectal cancer cells: a study in vitro and in vivo.
Cell Death Dis. 2017 May 25;8(5):e2815.
195.Zhang Y, Han L, Yang H, Pang J, Li P, Zhang G, Li F, Wang F.
Bisphenol A affects cell viability involved in autophagy and apoptosis in goat testis sertoli cell.
Environ Toxicol Pharmacol. 2017 Oct;55:137-147.
196.Xu XH, Liu QY, Li T, Liu JL, Chen X, Huang L, Qiang WA, Chen X, Wang Y, Lin LG, Lu JJ.
Garcinone E induces apoptosis and inhibits migration and invasion in ovarian cancer cells.
Sci Rep. 2017 Sep 6;7(1):10718.
197.Tian Q, Wang Y, Zhang Q, Luo J, Jiang H, Zhang B, Mei M, Wu F, Wu Y, Peng J, Long T, Luo Y, Guo X.
Phosphoprotein Gene Contributes tothe Enhanced Apoptosis Induced by Wild-Type RabiesVirus GD-SH-01 In Vitro.
Front Microbiol. 2017 Sep 5;8:1697.
198.Zhang Y, Cui P, Li Y, Feng G, Tong M, Guo L, Li T, Liu L, Li W, Zhou Q.
Mitochondrially produced ATP affects stem cell pluripotency via Actl6a-mediated histoneacetylation.
FASEB J. 2017 Dec 8. pii: fj.201700626RR.
199.Zhang J, Wang Y, Zhou Y, He QY.
Jolkinolide B induces apoptosis of colorectal carcinoma through ROS-ER stress-Ca2+-mitochondria dependent pathway.
Oncotarget. 2017 Aug 9;8(53):91223-91237.
200.Lin Z, Xu W, Li C, Wang Y, Yang L, Zou B, Gao S, Yao W, Song Z, Liu G.
β-8-Oxoguanine DNA Glycosylase Overexpression Reduces Oxidative Stress-InducedMitochondrial Dysfunction and Apoptosis Throughthe JNK Signaling Pathway in Human Bronchial Epithelial Cells.
DNA Cell Biol. 2017 Dec;36(12):1071-1080.
201.Wang Q, Wang H, Jia Y, Pan H, Ding H.
Luteolin induces apoptosis by ROS/ER stress and mitochondrial dysfunction in gliomablastoma.
Cancer Chemother Pharmacol. 2017 May;79(5):1031-1041.
202.Xu LQ, Lin MJ, Li YP, Li S, Chen SJ, Wei CJ.
Preparation of Plasma Membrane Vesicles from Bone Marrow Mesenchymal Stem Cells for Potential Cytoplasm Replacement Therapy.
J Vis Exp. 2017 May 18;(123). doi: 10.3791/55741.
203.Liu Y, Hu Y, E Q, Zuo J, Yang L, Liu W.
Salvianolic acid B inhibits mitochondrial dysfunction by up-regulating mortalin.
Sci Rep. 2017 Mar 2;7:43097.
204.An J, Zhang Y, He J, Zang Z, Zhou Z, Pei X, Zheng X, Zhang W, Yang H, Li S.
Lactate dehydrogenase A promotes the invasion and proliferation of pituitary adenoma.
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205.Zhou YZ, Li X, Gong WX, Tian JS, Gao XX, Gao L, Zhang X, Du GH, Qin XM.
Protective effect of isoliquiritin against corticosterone-induced neurotoxicity in PC12 cells.
Food Funct. 2017 Mar 22;8(3):1235-1244.
206.Jiang DQ, Wang Y, Li MX, Ma YJ, Wang Y.
SIRT3 in Neural Stem Cells Attenuates Microglia Activation-Induced Oxidative Stress Injury Through Mitochondrial Pathway.
Front Cell Neurosci. 2017 Jan 31;11:7.
207.Zhang C, Yuchi H, Sun L, Zhou X, Lin J.
Human amnion-derived mesenchymal stem cells protect against UVA irradiation-induced humandermal fibroblast senescence, in vitro.
Mol Med Rep. 2017 Aug;16(2):2016-2022.
208.Cao H, Xu H, Zhu G, Liu S.
Isoquercetin ameliorated hypoxia/reoxygenation-induced H9C2 cardiomyocyte apoptosis via a mitochondrial-dependent pathway.
Biomed Pharmacother. 2017 Nov;95:938-943.
209.Zhang JX, Wang R, Xi J, Shen L, Zhu AY, Qi Q, Wang QY, Zhang LJ, Wang FC, Lü HZ, Hu JG.
Morroniside protects SK-N-SH human neuroblastoma cells against H2O2-induced damage.
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210.Liu X, Lei J, Wang K, Ma L, Liu D, Du Y, Wu Y, Zhang S, Wang W, Ma X, Liu H.
Mitochondrial Omi/HtrA2 Promotes Caspase Activation Through Cleavage of HAX-1 in AgingHeart.
Rejuvenation Res. 2017 Jun;20(3):183-192.
211.Du JY, Yuan F, Zhao LY, Zhu J, Huang YY, Zhang GS, Wei Y, Liu Y, Yi Q, Tu YS, Zhong X, Sun FY, Sun HS, Guan YY, Chen WL, Wang GL.
Suppression of Kv1.5 protects against endothelial apoptosis induced by palmitate andin type 2diabetes mice.
Life Sci. 2017 Jan 1;168:28-37.
212.Tian SW, Ren Y, Pei JZ, Ren BC, He Y.
Pigment epithelium-derived factor protects retinal ganglion cells from hypoxia-inducedapoptosis by preventing mitochondrial dysfunction.
Int J Ophthalmol. 2017 Jul 18;10(7):1046-1054.
213.Guo HL, Hassan HM, Ding PP, Wang SJ, Chen X, Wang T, Sun LX, Zhang LY, Jiang ZZ.
Pyrazinamide-induced hepatotoxicity is alleviated by 4-PBA via inhibition ofthePERK-eIF2α-ATF4-CHOP pathway.
Toxicology. 2017 Mar 1;378:65-75.
214.Zhang M, Wang S, Cheng Z, Xiong Z, Lv J, Yang Z, Li T, Jiang S, Gu J, Sun D, Fan Y.
Polydatin ameliorates diabetic cardiomyopathy via Sirt3 activation.
Biochem Biophys Res Commun. 2017 Nov 25;493(3):1280-1287.
215.Xu XH, Zhang LL, Wu GS, Chen X, Li T, Chen X, Wang YT, Lu JJ.
Solasodine Induces Apoptosis, Affects Autophagy, and Attenuates Metastasis in Ovarian CancerCells.
Planta Med. 2017 Feb;83(3-04):254-260.
216.Wang Y, Yuan S, Li L, Yang D, Xu C, Wang S, Zhang D.
Novel proapoptotic agent SM-1 enhances the inhibitory effect of 5-fluorouracil on colorectalcancer cells in vitro and in vivo.
Oncol Lett. 2017 Jun;13(6):4762-4768.
217.Xu W, Yu H, Ma R, Ma L, Liu Q, Shan H, Wu C, Zhang R, Zhou Y, Shan H.
Apelin protects against myocardial ischemic injury by inhibiting dynamin-related protein 1.
Oncotarget. 2017 Oct 10;8(59):100034-100044.
218.Gao Y, Zhang J, Liu Y, Zhang S, Wang Y, Liu B, Liu H, Li R, Lv C, Song X.
Regulation of TERRA on telomeric and mitochondrial functions in IPF pathogenesis.
BMC Pulm Med. 2017 Dec 2;17(1):163.
219.Sun J, Jiang L, Lin Y, Gerhard EM, Jiang X, Li L, Yang J, Gu Z.
Enhanced anticancer efficacy of paclitaxel through multistage tumor-targeting liposomesmodified with RGD and KLA peptides.
Int J Nanomedicine. 2017 Feb 27;12:1517-1537.
220.Feng C, Xia Y, Zou P, Shen M, Hu J, Ying S, Pan J, Liu Z, Dai X, Zhuge W, Liang G, Ruan Y.
Curcumin analog L48H37 induces apoptosis through ROS-mediated endoplasmic reticulumstress and STAT3 pathways in human lung cancer cells.
Mol Carcinog. 2017 Jul;56(7):1765-1777.
221.Liu Y, Han M, Li X, Wang H, Ma M, Zhang S, Guo Y, Wang S, Wang Y, Duan N, Xu B, Yin J, Yao Y.
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222.Liu Y, Jiang Y, Wang N, Jin Q, Ji F, Zhong C, Zhang Z, Yang J, Ye X, Chen T.
Invalidation of mitophagy by FBP1-mediated repression promotes apoptosis in breast cancer.
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223.Du S, Li J, Du C, Huang Z, Chen G, Yan W.
Overendocytosis of superparamagnetic iron oxide particles increases apoptosis and triggersautophagic cell death in human osteosarcoma cell under a spinning magnetic field.
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224.Zhao L, Lin H, Chen S, Chen S, Cui M, Shi D, Wang B, Ma K, Shao Z.
Hydrogen peroxide induces programmed necrosis in rat nucleus pulposus cells through the RIP1/RIP3-PARP-AIF pathway.
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225.Hao M, Zhu S, Hu L, Zhu H, Wu X, Li Q.
Myocardial Ischemic Postconditioning Promotes Autophagy against Ischemia Reperfusion Injuryvia the Activation of the nNOS/AMPK/mTOR Pathway.
Int J Mol Sci. 2017 Mar 11;18(3). pii: E614.
226.Fu J, Yang Q, Li Y, Li P, Wang L, Li X.
A mechanism bywhich Astragalus polysaccharide protects against ROS toxicity through inhibiting the protein dephosphorylation of boar sperm preserved at 4 °C.
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227.Jie M, Mao S, Liu H, He Z, Li HF, Lin JM.
Evaluation of drug combination for glioblastoma based onan intestine-liver metabolic model on microchip.
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228.Hu J, Cui W, Ding W, Gu Y, Wang Z, Fan W.
Globular Adiponectin Attenuated H2O2-Induced Apoptosis in Rat Chondrocytes by InducingAutophagy Through the AMPK/ mTOR Pathway.
Cell Physiol Biochem. 2017;43(1):367-382.
229.Zhang J, Liu C, Huang RZ, Chen HF, Liao ZX, Sun JY, Xia XK, Wang FX.
Three new C-27-carboxylated-lupane-triterpenoid derivatives from Potentilla discolor Bunge and their in vitro antitumor activities.
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230.Liu J, Zhang Y, Chen L, Yu F, Li X, Dan Tao, Zhao J, Zhou S.
Polyphyllin I induces G2/M phase arrest and apoptosis in U251 human glioma cells viamitochondrial dysfunction and the JNK signaling pathway.
Acta Biochim Biophys Sin (Shanghai). 2017 Jun 1;49(6):479-486.
231.Wu L, Pang Y, Qin G, Xi G, Wu S, Wang X, Chen T.
Farnesylthiosalicylic acid sensitizes hepatocarcinoma cells to artemisinin derivatives.
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232.Weng J, Li W, Jia X, An W.
Alleviation of Ischemia-Reperfusion Injury in Liver Steatosis by Augmenter of LiverRegeneration Is Attributed to Antioxidation and Preservation of Mitochondria.
Transplantation. 2017 Oct;101(10):2340-2348.
233.Yan Y, Wang L, He J, Liu P, Lv X, Zhang Y, Xu X, Zhang L, Zhang Y.
Synergy with interferon-lambda 3 and sorafenib suppresses hepatocellular carcinomaproliferation.
Biomed Pharmacother. 2017 Apr;88:395-402.
234.Wu X, Jiang L, Sun X, Yao X, Bai Y, Liu X, Liu N, Zhai X, Wang S, Yang G.
Mono(2-ethylhexyl) phthalate induces autophagy-dependent apoptosis through lysosomal-mitochondrial axis in human endothelial cells.
Food Chem Toxicol. 2017 Aug;106(Pt A):273-282.
235.Zhu L, Li M, Liu X, Du L, Jin Y.
Inhalable oridonin-loaded poly(lactic-co-glycolic)acid large porous microparticles forin situtreatment of primary non-small cell lung cancer.
Acta Pharm Sin B. 2017 Jan;7(1):80-90.
236.Wang D, DanXu, Sun Y, Wu Y, Ma L, Duan J.
Synthesis, characterization and anticancer activity of tanshinone I grafted low molecularchitosan.
Glycoconj J. 2017 Feb;34(1):3-12.
237.Zhang Y, Liu L, Li F, Wu T, Jiang H, Jiang X, Du X, Wang Y.
Salinomycin Exerts Anticancer Effects on PC-3 Cells and PC-3-Derived Cancer Stem Cells In Vitro and In Vivo.
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238.Wang S, Mao Y, Xi S, Wang X, Sun L. Nutrient Starvation Sensitizes Human Ovarian Cancer SKOV3 Cells to BH3 Mimetic viaModulation of Mitochondrial Dynamics.
Anat Rec (Hoboken). 2017 Feb;300(2):326-339.
239.Qi G, Mi Y, Fan R, Zhao B, Ren B, Liu X.
Tea polyphenols ameliorates neural redox imbalance and mitochondrial dysfunction viamechanisms linking the key circadian regular Bmal1.
Food Chem Toxicol. 2017 Dec;110:189-199.
240.Li HJ, Sun XM, Li ZK, Yin QW, Pang H, Pan JJ, Li X, Chen W.
LncRNA UCA1 Promotes Mitochondrial Function of Bladder Cancer via the MiR-195/ARL2Signaling Pathway.
Cell Physiol Biochem. 2017;43(6):2548-2561.
241.Hu S, Gao Y, Zhou H, Kong F, Xiao F, Zhou P, Chen Y.
New insight into mitochondrial changes in vascular endothelial cells irradiated by gamma ray.
Int J Radiat Biol. 2017 May;93(5):470-476.
242.Ye R, Xu S, Liu Y, Pang L, Lian X, Zhong Y, Su Y, Wang S.
Protective Effect of Icariin onthe Development of Preimplantation Mouse Embryos againstHydrogen Peroxide-Induced Oxidative Injury.
Oxid Med Cell Longev. 2017;2017:2704532.
243.Deng M, Qin Y, Chen X, Li D, Wang Q, Zheng H, Gu L, Deng C, Xue Y, Zhu D, Wang Q, Wang J.
Combination of celecoxib and PD184161 exerts synergistic inhibitory effects on gallbladdercancer cell proliferation.
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244.Zhang YH, Li J, Yang WZ, Xian ZH, Feng QT, Ruan XC.
Mitochondrial expression and activity of P-glycoprotein under oxidative stress in outer blood-retinal barrier.
Int J Ophthalmol. 2017 Jul 18;10(7):1055-1063.
245.Yang RX, Lei J, Wang BD, Feng DY, Huang L, Li YQ, Li T, Zhu G, Li C, Lu FF, Nie TJ, Gao GD, Gao L.
Pretreatment with Sodium Phenylbutyrate Alleviates Cerebral Ischemia/Reperfusion Injury by Upregulating DJ-1 Protein.
Front Neurol. 2017 Jun 9;8:256.
246.Liu Q, Zhou Y, Duan R, Wei H, Jiang S, Peng J.
Lower dietary n-6 : n-3 ratio and high-dose vitamin E supplementation improve spermmorphology and oxidative stress in boars.
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247.Huang H, Guo M, Liu N, Zhao C, Chen H, Wang X, Liao S, Zhou P, Liao Y, Chen X, Lan X, Chen J, Xu D, Li X, Shi X, Yu L, Nie Y, Wang X, Zhang CE, Liu J.
Bilirubin neurotoxicity is associated with proteasome inhibition.
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248.Li L, Ni J, Li M, Chen J, Han L, Zhu Y, Kong D, Mao J, Wang Y, Zhang B, Zhu M, Gao X, Fan G.
Ginsenoside Rg3 micelles mitigate doxorubicin-induced cardiotoxicity and enhance its anticancer efficacy.
Drug Deliv. 2017 Nov;24(1):1617-1630.
249.Li H, Wang Y, Wang C, Zhang S, Li S, Zhou G, Wang S, Zhang J.
Extraction, selenylation modification and antitumor activity ofthe glucan from Castaneamollissima Blume.
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250.Liu Z, Ren B, Wang Y, Zou C, Qiao Q, Diao Z, Mi Y, Zhu D, Liu X.
Sesamol Induces Human Hepatocellular Carcinoma Cells Apoptosis by Impairing MitochondrialFunction and Suppressing Autophagy.
Sci Rep. 2017 Apr 4;7:45728.
251.Yang J, Yu J, Li D, Yu S, Ke J, Wang L, Wang Y, Qiu Y, Gao X, Zhang J, Huang L.
Store-operated calcium entry-activated autophagy protects EPC proliferation via the CAMKK2-MTOR pathway in ox-LDL exposure.
Autophagy. 2017 Jan 2;13(1):82-98.
252.Di G, Zhao X, Qi X, Zhang S, Feng L, Shi W, Zhou Q.
VEGF-B promotes recovery of corneal innervations and trophic functions in diabetic mice.
Sci Rep. 2017 Jan 16;7:40582.
253.Huang X, Huang R, Gou S, Wang Z, Liao Z, Wang H.
Platinum(IV) complexes conjugated with phenstatin analogue as inhibitors of microtubulepolymerization and reverser of multidrug resistance.
Bioorg Med Chem. 2017 Sep 1;25(17):4686-4700.
254.Lu Y, Ma W, Li Z, Lu J, Wang X.
The interplay between p16 serine phosphorylation and arginine methylation determines its function in modulating cellular apoptosis and senescence.
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255.Zhu H, Chen Z, Ma Z, Tan H, Xiao C, Tang X, Zhang B, Wang Y, Gao Y.
Tanshinone IIA Protects Endothelial Cells from H₂O₂-Induced Injuries via PXR Activation.
Biomol Ther (Seoul). 2017 Nov 1;25(6):599-608.
256.Zhao J, Liao Y, Chen J, Dong X, Gao Z, Zhang H, Wu X, Liu Z, Wu Y.
Aberrant Buildup of All-Trans-Retinal Dimer, a Nonpyridinium Bisretinoid Lipofuscin Fluorophore, Contributes tothe Degeneration ofthe Retinal Pigment Epithelium.
Invest Ophthalmol Vis Sci. 2017 Feb 1;58(2):1063-1075.
257.He X, Li S, Liu B, Susperreguy S, Formoso K, Yao J, Kang J6, Shi A7, Birnbaumer L8,9, Liao Y.
Major contribution ofthe 3/6/7 class of TRPC channels to myocardial ischemia/reperfusion and cellular hypoxia/reoxygenation injuries.
Proc Natl Acad Sci U S A. 2017 Jun 6;114(23):E4582-E4591.
258.Xiao J, Zhang R, Huang F, Liu L, Deng Y, Ma Y, Wei Z, Tang X, Zhang Y, Zhang M.
Lychee (Litchi chinensis Sonn.) Pulp Phenolic Extract Confers a Protective Activity againstAlcoholic Liver Disease in Mice by Alleviating Mitochondrial Dysfunction.
J Agric Food Chem. 2017 Jun 21;65(24):5000-5009.
259.Chang G, Liu J, Qin S, Jiang Y, Zhang P, Yu H, Lu K, Zhang N, Cao L, Wang Y, Li Y, Zhang D.
Cardioprotection by exenatide:A novel mechanism via improving mitochondrial functioninvolving the GLP-1 receptor/cAMP/PKA pathway.
Int J Mol Med. 2018 Mar;41(3):1693-1703.
260.Yin J, Ni B, Liao WG, Gao YQ.
Hypoxia-induced apoptosis of mouse spermatocytes is mediated byHIF-1αthrougha deathreceptor pathway and a mitochondrial pathway.
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261.Yang F, Li T, Dong Z, Mi R.
MicroRNA-410 is involved in mitophagy after cardiac ischemia/reperfusion injury by targetinghigh-mobility group box 1 protein.
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262.Qiu M, Shi F, Dai F, Song R, Wang S, You Y, Zhao B.
A reactive oxygen species activation mechanism contributes to Sophoridine-induced apoptosis in rat liver BRL-3A cells.
J Ethnopharmacol. 2018 Mar 1;213:376-383.
263.Zhang YF, Su PK, Wang LJ, Zheng HQ, Bai XF, Li P, Meng XP, Yang JY.
T-2 toxin induces apoptosis via the Bax-dependent caspase-3 activation in mouse primaryLeydig cells.
Toxicol Mech Methods. 2018 Jan;28(1):23-28.
264.Bian X, Teng T, Zhao H, Qin J, Qiao Z, Sun Y, Liun Z, Xu Z.
Zinc prevents mitochondrial superoxide generation by inducing mitophagy inthe setting of hypoxia/reoxygenation in cardiac cells.
Free Radic Res. 2018 Jan;52(1):80-91.
265.Wang Y, Zhao Y, Jiang W, Zhao X, Fan G, Zhang H, Shen P, He J, Fan X.
iTRAQ-based proteomic analysis reveals recovery of impaired mitochondrial function in ischemic myocardium by Shenmai formula.
J Proteome Res. 2018 Feb 2;17(2):794-803.
266.Dai C, Ciccotosto GD, Cappai R, Wang Y, Tang S, Hoyer D, Schneider EK, Velkov T, Xiao X.
Rapamycin Confers Neuroprotection against Colistin-Induced Oxidative Stress, MitochondriaDysfunction,and Apoptosis throughthe Activation of Autophagy and mTOR/Akt/CREB Signaling Pathways.
ACS Chem Neurosci. 2018 Apr 18;9(4):824-837.