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感受态制备 |T载体、质粒 |基因突变
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 JC-1

  产品编号C2005
  产品包装: 1mg
  产品价格: 791.00元
产品编号 产品名称 产品包装 产品价格
C2005 JC-1 1mg 791.00元

      JC-1也称CBIC2(3)或5,5′,6,6′-Tetrachloro-1,1′,3,3′-tetraethyl-imidacarbocyanine iodide,分子式为C25H27Cl4IN4,分子量为652.23,CAS Number 3520-43-2,纯度>95%。
      JC-1是一种广泛用于检测线粒体膜电位(mitochondrial membrane potential)△Ψm 的理想荧光探针。可以检测细胞、组织或纯化的线粒体膜电位。在线粒体膜电位较高时,JC-1聚集在线粒体的基质(matrix)中,形成聚合物(J-aggregates),可以产生红色荧光;在线粒体膜电位较低时,JC-1不能聚集在线粒体的基质中,此时JC-1为单体(monomer),可以产生绿色荧光。这样就可以非常方便地通过荧光颜色的转变来检测线粒体膜电位的变化。常用红绿荧光的相对比例来衡量线粒体去极化的比例。
      线粒体膜电位的下降是细胞凋亡早期的一个标志性事件。通过JC-1从红色荧光到绿色荧光的转变可以很容易地检测到细胞膜电位的下降,同时也可以用JC-1从红色荧光到绿色荧光的转变作为细胞凋亡早期的一个检测指标。
      JC-1单体的最大激发波长为514nm,最大发射波长为529nm;JC-1聚合物(J-aggregates)的最大激发波长为585nm,最大发射波长为590nm。实际观察时,使用常规的观察红色荧光和绿色荧光的设置即可。
      JC-1稀释和使用时有一些特殊的要求,因此对于初次使用JC-1的用户或对于JC-1的使用不是非常熟悉的用户,我们建议使用碧云天的线粒体膜电位检测试剂盒(JC-1)(C2006),该试剂盒配套提供了一些相关试剂,使用起来更加便捷。
      本JC-1溶解在DMSO中,浓度为5mg/ml,共200μl。
包装清单:

产品编号 产品名称 包装
C2005 JC-1(5mg/ml) 50μl/管,共4管
说明书 1份

保存条件:
      -20℃避光保存。
注意事项:
      JC-1如果一次使用量较小,需把每管再适当进行分装,尽量避免反复冻融。
      JC-1在4℃、冰浴等较低温度情况下会凝固而粘在离心管管底、管壁或管盖内,可以20-25℃水浴温育片刻至全部融解后使用。
      本产品仅限于专业人员的科学研究用,不得用于临床诊断或治疗,不得用于食品或药品,不得存放于普通住宅内。
      为了您的安全和健康,请穿实验服并戴一次性手套操作。

使用说明:
JC-1用于检测细胞的线粒体膜电位时常用的浓度范围为1-20μg/ml,对于很多细胞适宜采用的JC-1浓度为10μg/ml。详细的使用方法请参考相关文献资料。
相关产品请点击如下按钮:
使用本产品的文献:
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Toxic effect of different ZnO particles on mouse alveolar macrophages.
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72.Lin CJ, Huang HC, Liu WJ, Jiang ZF.
Biomedical Imaging and Visualization Model of Mitochondrial Dysfunction and Oxidative Stress in Alzheimer Disease.
Applied Mechanics and Materials. 2012;138-9:1179-82 .
73.Ge H, Tollner TL, Hu Z, Da M, Li X, Guan H, Shan D, Lu J, Huang C, Dong Q.
Impaired mitochondrial function in murine oocytes is associated with controlled ovarian hyperstimulation and invitro maturation.
Reprod Fertil Dev. 2012;24(7):945-52.
74.Lei JC, Yu JQ, Yin Y, Liu YW, Zou GL.
Alantolactone induces activation of apoptosis in human hepatoma cells.
Food Chem Toxicol. 2012 Sep;50(9):3313-9. 
75.Jia Y, Dong X, Zhou P, Liu X, Pan L, Xin H, Zhu YZ, Wang Y.
The synthesis and biological evaluation of novel Danshensu-cysteine analog conjugates as cardiovascular-protective agents.
Eur J Med Chem.2012 Sep;55:176-87.
76.Dai T, Zhao E, Lu G, Che K, He Q, Lu Y, Fang Q, Wang H, Zheng L, Li S, Huang C, Dong Q.
Sperm cryopreservation of yellow drum Nibea albiflora: A special emphasis on post-thaw sperm quality.
Aquaculture.2012 Nov;368-369:82-8. 
77.Tu J, Wang T, Shi W, Wu G, Tian X, Wang Y, Ge D, Ren L.
Multifunctional ZnPc-loaded mesoporous silica nanoparticles for enhancement of photodynamic therapy efficacyby endolysosomal escape.
Biomaterials. 2012 Nov;33(31):7903-14.
78.Chen C, Han S, Liu W, Wang Y, Huang G.
Effect of vitrification on mitochondrial membrane potential in human metaphase II oocytes.
J Assist Reprod Genet. 2012 Oct;29(10):1045-50. 
79.Yuan L, Wang J, Xiao H, Xiao C, Wang Y, Liu X.
Isoorientin induces apoptosis through mitochondrial dysfunction and inhibition of PI3K/Akt signaling pathway inHepG2 cancer cells.
Toxicol Appl Pharmacol. 2012 Nov 15;265(1):83-92.
80.Li GQ, Chen XG, Wu XP, Xie JD, Liang YJ, Zhao XQ, Chen WQ, Fu LW.
Effect of dicycloplatin, a novel platinum chemotherapeutical drug, on inhibiting cell growth and inducing cellapoptosis.
PLoS One. 2012;7(11):e48994.
81.Ma ZY, Qiao X, Xie CZ, Shao J, Xu JY, Qiang ZY, Lou JS.
Activities of a novel Schiff Base copper(II) complex on growth inhibition and apoptosis induction toward MCF-7human breast cancer cells via mitochondrial pathway.
J Inorg Biochem. 2012 Dec;117:1-9.
82.Lin F, Xu W, Guan C, Zhou M, Hong W, Fu L, Liu D, Xu A.
Niacin protects against UVB radiation-induced apoptosis in cultured human skin keratinocytes.
Int J Mol Med. 2012 Apr;29(4):593-600.
83.Miao H, Zhao L, Li C, Shang Q, Lu H, Fu Z, Wang L, Jiang Y, Cao Y.
Inhibitory effect of Shikonin on Candida albicans growth.
Biol Pharm Bull. 2012;35(11):1956-63.
84.Shi CM, Wang YM, Zhang CM, Qiu J, Shen YH, Zhu JG, Chen L, Xu GF, Zhao YP, Ji CB, Guo XR.
Knockdown of NYGGF4 (PID1) rescues insulin resistance and mitochondrial dysfunction induced by FCCP in3T3-L1 adipocytes.
Mitochondrion.2012 Nov;12(6):600-6.
85.Zhao X, Cong X, Zheng L, Xu L, Yin L, Peng J.
Dioscin, a natural steroid saponin, shows remarkable protective effect against acetaminophen-induced liverdamage in vitro and in vivo.
Toxicol Lett. 2012 Oct 2;214(1):69-80.
86.Ru Y, Yin L, Sun H, Yin S, Pan Q, Wei H, Wu L, Liu S.
A micropreparation of mitochondria from cells using magnetic beads with immunoaffinity.
Anal Biochem.2012 Feb 1;421(1):219-26.
87.Yu H, Li X, Sun S, Gao X, Zhou D.
c-Met inhibitor SU11274 enhances the response of the prostate cancer cell line DU145 to ionizing radiation.
Biochem Biophys Res Commun. 2012 Oct 26;427(3):659-65. 
88.Liu Q, Yao JY, Qian C, Chen R, Li XY, Liu SW, Sun BG, Song LS, Hong J.
Effects of propofol on ischemia-induced ventricular arrhythmias and mitochondrial ATP-sensitive potassium channels.
Acta Pharmacol Sin. 2012 Dec;33(12):1495-501.
89.Chen XM, Liu J, Wang T, Shang J.
Colchicine-induced apoptosis in human normal liver L-02 cells by mitochondrial mediated pathways.
Toxicol In Vitro.2012 Aug;26(5):649-55.
90.Zhu X, Chen C, Ye D, Guan D, Ye L, Jin J, Zhao H, Chen Y, Wang Z, Wang X, Xu Y.
Diammonium glycyrrhizinate upregulates PGC-1α and protects against Aβ1-42-induced neurotoxicity.
PLoS One. 2012;7(4):e35823.
91.Zhang W, Huang Q, Hua Z.
Galangin and TRAIL cooperate to suppress A549 lung cancer proliferation via apoptosis and p38 MAPK activation.
Acta Pharmaceutica Sinica B. 2012 Dec;2(6):569-74.
92.Wang CQ, Zhang J, Sun YF, Wang D, Li CJ, Li WH, Lu C, Liu Z, Wu H, Hou XF, Chen C, Zhou X.
Detection of Neurotrophin-4 (NT-4) in Ejaculated Bull Spermatozoa and its Effect on SpermatozoaMitochondrial Activity.
Reprod Domest Anim.  2013 Feb;48(1):131-6.
93.Wei Z, Yuan S, Hao J, Fang X.
Mechanism of inhibition of P-glycoprotein mediated efflux by Pluronic P123/F127 block copolymers: Relationship between copolymer concentration and inhibitory activity.
Eur J Pharm Biopharm. 2013 Feb;83(2):266-73.
94.Mao Z, Xia W, Wang J, Chen T, Zeng Q, Xu B, Li W, Chen X, Xu S.
Perfluorooctane sulfonate induces apoptosis in lung cancer A549 cells through reactive oxygen species-mediated mitochondrion-dependent pathway.
J Appl Toxicol. 2013 Nov;33(11):1268-76.
95.Zhang L, Sang H, Liu Y, Li J.
Manganese activates caspase-9-dependent apoptosis in human bronchial epithelial cells.
Hum Exp Toxicol. 2013 Nov;32(11):1155-63.
96.Shi CM, Xu GF, Yang L, Fu ZY, Chen L, Fu HL, Shen YH, Zhu L, Ji CB, Guo XR.
Overexpression of TFAM Protects 3T3-L1 Adipocytes from NYGGF4 (PID1) Overexpression-Induced InsulinResistance and Mitochondrial Dysfunction.
Cell Biochem Biophys. 2013 Jul;66(3):489-97.
97.Zhang X, Xie P, Zhang X, Zhou W, Zhao S, Zhao Y, Cai Y.
Toxic effects of microcystin-LR on the HepG2 cell line under hypoxic and normoxic conditions.
J Appl Toxicol. 2013 Oct;33(10):1180-6.
98.Hu Y, Qi Y, Liu H, Fan G, Chai Y.
Effects of celastrol on human cervical cancer cells as revealed by ion-trap gas chromatography-massspectrometry based metabolic profiling.
Biochim Biophys Acta. 2013 Mar;1830(3):2779-89.
99.Guo D, Bi H, Liu B, Wu Q, Wang D, Cui Y.
Reactive oxygen species-induced cytotoxic effects of zinc oxide nanoparticles in rat retinal ganglion cells.
Toxicol In Vitro.2013 Mar;27(2):731-8.
100.Yue B, Zhang YS, Xu HM, Zhao CR, Li YY, Qin YZ, Wang RQ, Sun D, Yuan Y, Lou HX, Qu XJ.
Riccardin D-26, a synthesized macrocyclic bisbibenzyl compound, inhibits human hepatocellular carcinoma growth through induction of apoptosis in p53-dependent way.
Cancer Lett. 2013 Jan 1;328(1):104-13.
101.Wang F, Gao Q, Guo S, Cheng J, Sun X, Li Q, Wang T, Zhang Z, Cao W, Tian Y.
The sonodynamic effect of curcumin on THP-1 cell-derived macrophages.
Biomed Res Int. 2013;2013:737264.
102.Pi J, Jin H, Liu R, Song B, Wu Q, Liu L, Jiang J, Yang F, Cai H, Cai J.
Pathway of cytotoxicity induced by folic acid modified selenium nanoparticles in MCF-7 cells.
Appl Microbiol Biotechnol. 2013 Feb;97(3):1051-62.
103.Song S, Wang S, Ma J, Yao L, Xing H, Zhang L, Liao L, Zhu D.
Biliverdin reductase/bilirubin mediates the anti-apoptotic effect of hypoxia in pulmonary arterial smooth musclecells through ERK1/2 pathway.
Exp Cell Res.2013 Aug 1;319(13):1973-87.
104.Yang Y, Yan X, Duan W, Yan J, Yi W, Liang Z, Wang N, Li Y, Chen W, Yu S, Jin Z, Yi D.
Pterostilbene Exerts Antitumor Activity via the Notch1 Signaling Pathway in Human Lung Adenocarcinoma Cells.
PLoS One. 2013 May 3;8(5):e62652.
105.Liang D, Xiang L, Yang M, Zhang X, Guo B, Chen Y, Yang L, Cao J.
ZnT7 can protect MC3T3-E1 cells from oxidative stress-induced apoptosis via PI3K/Akt and MAPK/ERK signalingpathways.
Cell Signal. 2013 May;25(5):1126-35.
106.Fan Y, Wang C, Zhang Y, Hang P, Liu Y, Pan Z, Wang N, Du Z.
Genistein ameliorates adverse cardiac effects induced by arsenic trioxide through preventing cardiomyocytesapoptosis.
Cell Physiol Biochem. 2013;31(1):80-91.
107.Sun S, Pan S, Miao A, Ling C, Pang S, Tang J, Chen D, Zhao C.
Active extracts of black tea (Camellia Sinensis) induce apoptosis of PC-3 prostate cancer cells via mitochondrialdysfunction.
Oncol Rep. 2013 Aug;30(2):763-72.
108.Li P, Xue Y, Zhang W, Teng F, Sun Y, Qu T, Chen X, Cheng X, Song B, Luo W, Yu Q.
Sodium fluoride induces apoptosis in odontoblasts via a JNK-dependent mechanism.
Toxicology. 2013 Jun 7;308:138-45.
109.Liu Y, Wang L, Wu Y, Lv C, Li X, Cao X, Yang M, Feng D, Luo Z.
Pterostilbene exerts antitumor activity against human osteosarcoma cells by inhibiting the JAK2/STAT3 signalingpathway.
Toxicology. 2013 Feb 8;304:120-31.
110.Tang Q, Li G, Wei X, Zhang J, Chiu JF, Hasenmayer D, Zhang D, Zhang H.
Resveratrol-induced apoptosis is enhanced by inhibition of autophagy in esophageal squamous cell carcinoma.
Cancer Lett.2013 Aug 19;336(2):325-37.
111.Chen Y, Zhuang X, Xu Z, Lu L, Guo H, Wu W, Liao X.
Higenamine Combined with [6]-Gingerol Suppresses Doxorubicin-Triggered Oxidative Stress and Apoptosis in Cardiomyocytes via Upregulation of PI3K/Akt Pathway.
Evidence-Based Complementary and Alternative Medicine.2013;2013:970490.
112.Ma J, Zhang L, Zhang J, Liu M, Wei L, Shen T, Ma C, Wang Y, Chen Y, Zhu D.
15-lipoxygenase-1/15-hydroxyeicosatetraenoic acid promotes hepatocellular cancer cells growth through protein kinase B and heat shock protein 90 complex activation.
Int J Biochem Cell Biol. 2013 Jun;45(6):1031-41.
113.Cai B, Li X, Wang Y, Liu Y, Yang F, Chen H, Yin K, Tan X, Zhu J, Pan Z, Wang B, Lu Y.
Apoptosis of bone marrow mesenchymal stem cells caused by homocysteine via activating JNK signal.
PLoS One. 2013 May 7;8(5):e63561.
114.Wu C, Wang C, Han T, Zhou X, Guo S, Zhang J.
Insight into the Cellular Internalization and Cytotoxicity of Graphene Quantum Dots.
Adv Healthc Mater. 2013 Dec;2(12):1613-9.
115.Ma LS, Jiang CY, Cui M, Lu R, Liu SS, Zheng BB, Li L, Li X.
Fluopsin C induces oncosis of human breast adenocarcinoma cells.
Acta Pharmacol Sin.2013 Aug;34(8):1093-100.
116.Sun L, Zhao M, Yu XJ, Wang H, He X, Liu JK, Zang WJ.
Cardioprotection by acetylcholine: a novel mechanism via mitochondrial biogenesis and function involving the PGC-1α pathway.
J Cell Physiol. 2013 Jun;228(6):1238-48.
117.Yuan F, Dong P, Wang X, Fu X, Dai M, Zhang W.
Toxicological effects of cigarette smoke on Ana-1 macrophages in vitro.
Exp Toxicol Pathol.2013 Nov;65(7-8):1011-8.
118.Li T, Liu Z, Jiang K, Ruan Q.
Angiopoietin2 enhances doxorubin resistance in HepG2 cells by upregulating survivin and Ref-1 via MSK1activation.
Cancer Lett.2013 Sep 1;337(2):276-84.
119.Wu WY, Wang WY, Ma YL, Yan H, Wang XB, Qin YL, Su M, Chen T, Wang YP.
Sodium tanshinone IIA silate inhibits oxygen-glucose deprivation/recovery-induced cardiomyocyte apoptosis viasuppression of the NF-κB/TNF-α pathway.
Br J Pharmacol. 2013 Jul;169(5):1058-71.
120.Zheng J, Zhang Y, Xu W, Luo Y, Hao J, Shen XL, Yang X, Li X, Huang K.
Zinc protects HepG2 cells against the oxidative damage and DNA damage induced by ochratoxin A.
Toxicol Appl Pharmacol. 2013 Apr 15;268(2):123-31.
121.E Q, Liu X, Liu Y, Liu W, Zuo J.
Over-expression of GRP75 inhibits liver injury induced by oxidative damage.
Acta Biochim Biophys Sin (Shanghai). 2013 Feb;45(2):129-34.
122.Yi F, He X, Wang D.
Lycopene Protects Against MPP+-Induced Cytotoxicity by Maintaining Mitochondrial Function in SH-SY5Y Cells.
Neurochem Res. 2013 Aug;38(8):1747-57.
123.Guo R, Liu B, Zhou S, Zhang B, Xu Y.
The protective effect of fasudil on the structure and function of cardiac mitochondria from rats with type 2 diabetes induced by streptozotocin with a high-fat diet is mediated by the attenuation of oxidative stress.
Biomed Res Int. 2013;2013:430791.
124.Li JW, Ning N, Ma YZ, Zhang R, Tan F, Chen NH.
Claulansine F suppresses apoptosis induced by sodium nitroprusside in PC12 cells.
Free Radic Res. 2013 Jul;47(6-7):488-97.
125.Wang Q,X Cheng X,Zhang D, Gao X, Zhou L, Qin X, Xie G, Liu K, Qin Y, Liu B, Qin M.
Tectorigenin Attenuates Palmitate-Induced Endothelial Insulin Resistance via Targeting ROS-Associated Inflammation and IRS-1 Pathway.
PLOS ONE.2013 Jun 19;8(6):e66417.
126.Jiang L, Liu Y, Ma MM, Tang YB, Zhou JG, Guan YY.
Mitochondria dependent pathway is involved in the protective effect of bestrophin-3 on hydrogen peroxide-induced apoptosis in basilar artery smooth muscle cells.
Apoptosis. 2013 May;18(5):556-65.
127.Huang H, Wu K, You Q, Huang R, Li S, Wu K.
Naringin inhibits high glucose-induced cardiomyocyte apoptosis by attenuating mitochondrial dysfunction andmodulating the activation of the p38 signaling pathway.
Int J Mol Med. 2013 Aug;32(2):396-402.
128.Zhou D, Wei A, Cao C, Ruan J.
DICO, a novel nonaromatic B-ring flavonoid, induces G2/M cell cycle arrest and apoptosis in human hepatomacells.
Food Chem Toxicol.2013 Jul;57:322-9.
129.Luo CL, Chen XP, Li LL, Li QQ, Li BX, Xue AM, Xu HF, Dai DK, Shen YW, Tao LY, Zhao ZQ.
Poloxamer 188 attenuates in vitro traumatic brain injury-induced mitochondrial and lysosomal membranepermeabilization damage in cultured primary neurons.
J Neurotrauma. 2013 Apr 1;30(7):597-607.
130.Li X, Tao H, Xie K, Ni Z, Yan Y, Wei K, Chuang PY, He JC, Gu L.
cAMP signaling prevents podocyte apoptosis via activation of protein kinase A and mitochondrial fusion.
PLoS One. 2014 Mar 18;9(3):e92003.
131.Sun J, Bai S, Bai W, Zou F, Zhang L, Li G, Hu Y, Li M, Yan R, Su Z, Huang Y.
1,3-Dichloro-2-propanol inhibits progesterone production through the expression of steroidogenic enzymes and cAMP concentration in Leydig cells.
Food Chem. 2014 Jul 1;154:330-6.
132.Chang C, Wu G, Gao P, Yang L, Liu W, Zuo J.
Upregulated Parkin expression protects mitochondrial homeostasis in DJ-1 konckdown cells and cells overexpressing the DJ-1 L166P mutation.
Mol Cell Biochem. 2014 Feb;387(1-2):187-95.
133.Yang L, Di G, Qi X, Qu M, Wang Y, Duan H, Danielson P, Xie L, Zhou Q.
Substance P promotes diabetic corneal epithelial wound healing through molecular mechanisms mediated via the neurokinin-1 receptor.
Diabetes.2014 Dec;63(12):4262-74.
134.Li D, Ye Y, Lin S, Deng L, Fan X, Zhang Y, Deng X, Li Y, Yan H, Ma Y.
Evaluation of deoxynivalenol-induced toxic effects on DF-1 cells in vitro: cell-cycle arrest, oxidative stress, and apoptosis.
Environ Toxicol Pharmacol. 2014 Jan;37(1):141-9.
135.He M, Dong C, Xie Y, Li J, Yuan D, Bai Y, Shao C.
Reciprocal bystander effect between α-irradiated macrophage and hepatocyte is mediated by cAMP through a membrane signaling pathway.
Mutat Res Fundam Mol Mech Mutagen. 2014 Mar 20;763-764C:1-9.
136.Tang C, Liang J, Qian J, Jin L, Du M, Li M, Li D.
Opposing role of JNK-p38 kinase and ERK1/2 in hydrogen peroxide-induced oxidative damage of human trophoblast-like JEG-3 cells.
Int J Clin Exp Pathol. 2014 Feb 15;7(3):959-68.
137.Chu JH, Zhao CR, Song ZY, Wang RQ, Qin YZ, Li WB, Qu XJ.
1082-39, an analogue of sorafenib, inhibited human cancer cell growth more potently than sorafenib.
Biomed Pharmacother. 2014 Apr;68(3):335-41.
138.Pan H, Cheng L, Yang H, Zou W, Cheng R, Hu T.
Lysophosphatidic acid rescues human dental pulp cells from ischemia-induced apoptosis.
J Endod. 2014 Feb;40(2):217-22. 
139.Zheng L, Sun X, Zhu X, Lv F, Zhong Z, Zhang F, Guo W, Cao W, Yang L, Tian Y.
Apoptosis of THP-1 derived macrophages induced by sonodynamic therapy using a new sonosensitizer hydroxyl acetylated curcumin.
PLoS One. 2014 Mar 27;9(3):e93133.
140.Cui SX, Zhang HL, Xu WF, Qu XJ.
13F-1, a novel 5-fluorouracil prodrug containing an Asn-Gly-Arg (NO2) COOCH3 tripeptide, inhibits human colonic carcinoma growth by targeting Aminopeptidase N (APN/CD13).
Eur J Pharmacol. 2014 Jul 5;734:50-9.
141.Fang L, Bai C, Chen Y, Dai J, Xiang Y, Ji X, Huang C, Dong Q.
Inhibition of ROS production through mitochondria-targeted antioxidant and mitochondrial uncoupling increases post-thaw sperm viability in yellow catfish.
Cryobiology.2014 Dec;69(3):386-93.
142.Wang C, Xia W, Jiang Q, Xu Y, Yu P.
Differential effects of lipid fractions from silver carp brain on human cervical carcinoma cells in vitro.
Food Funct. 2014 Sep;5(9):2194-201.
143.Fan S, Li X, Lin J, Chen S, Shan J, Qi G.
Honokiol inhibits tumor necrosis factor-α-stimulated rat aortic smooth muscle cell proliferation via caspase- and mitochondrial-dependent apoptosis.
Inflammation. 2014 Feb;37(1):17-26.
144.Guo P, Pi H, Xu S, Zhang L, Li Y, Li M, Cao Z, Tian L, Xie J, Li R, He M, Lu Y, Liu C, Duan W, Yu Z, Zhou Z.
Melatonin Improves Mitochondrial Function by Promoting MT1/SIRT1/PGC-1 Alpha-Dependent Mitochondrial Biogenesis in Cadmium-Induced Hepatotoxicity In Vitro.
Toxicol Sci. 2014;142(1):182-95.
145.Li D, Ma H, Ye Y, Ji C, Tang X, Ouyang D, Chen J, Li Y, Ma Y.
Deoxynivalenol induces apoptosis in mouse thymic epithelial cells through mitochondria-mediated pathway.
Environ Toxicol Pharmacol. 2014 Jul;38(1):163-71.
146.Liu L, Li T, Tan J, Fu J, Guo Q, Ji H, Zhang Y.
NG as a novel nitric oxide donor induces apoptosis by increasing reactive oxygen species and inhibiting mitochondrial function in MGC803 cells.
Int Immunopharmacol. 2014 Aug 16;23(1):27-36.
147.Zhang X, Yu Q, Jiang W, Bi Y, Zhang Y, Gong M, Wei X, Li T, Chen J.
All-trans retinoic acid suppresses apoptosis in PC12 cells injured by oxygen and glucose deprivation via the retinoic acid receptor α signaling pathway.
Mol Med Rep. 2014 Nov;10(5):2549-55.
148.Jiang L, Zhao MN, Liu TY, Wu XS, Weng H, Ding Q, Shu YJ, Bao RF, Li ML, Mu JS, Wu WG, Ding QC, Cao Y, Hu YP, Shen BY, Tan ZJ, Liu YB.
Bufalin induces cell cycle arrest and apoptosis in gallbladder carcinoma cells.
Tumour Biol. 2014 Nov;35(11):10931-41.
149.Sun ZB, Wang JW, Xiao H, Zhang QS, Kan WS, Mo FB, Hu S, Ye SN.
Icariin may benefit the mesenchymal stem cells of patients with steroid-associated osteonecrosis by ABCB1-promoter demethylation: a preliminary study.
Osteoporos Int.2015 Jan;26(1):187-97.
150.Pan HY, Yang H, Shao MY, Xu J, Zhang P, Cheng R, Hu T.
Sphingosine-1-phosphate mediates AKT/ERK maintenance of dental pulp homoeostasis.
Int Endod J. 2015;48(5):460-468.
151.Liu Y, Jiao R, Ma ZG, Liu W, Wu QQ, Yang Z, Li FF, Yuan Y, Bian ZY, Tang QZ.
Sanguinarine inhibits angiotensin II-induced apoptosis in H9c2 cardiac cells via restoring reactive oxygen species-mediated decreases in the mitochondrial embrane potential.
Mol Med Rep.2015 Sep;12(3):3400-8.
152.Duan C, Zhang B, Deng C, Cao Y, Zhou F, Wu L, Chen M, Shen S, Xu G, Zhang S, Duan G, Yan H, Zou X.
Piperlongumine induces gastric cancer cell apoptosis and G2/M cell cycle arrest both in vitro and in vivo.
Tumour Biol. 2016 Aug;37(8):10793-804.
153.Wang L, Qin W, Zhang J, Bao C, Zhang H, Che Y, Sun C, Gu J, Feng X, Du C, Han W, Richard PL, Lei L.
Adh enhances Actinobacillus pleuropneumoniae pathogenicity by binding to OR5M11 and activating p38which induces apoptosis of PAMs and IL-8 release.
Sci Rep. 2016 Apr 5;6:24058.
154.Li Y, Sun Y, Jing L, Wang J, Yan Y, Feng Y, Zhang Y, Liu Z, Ma L, Diao A.
Lysosome Inhibitors Enhance the Chemotherapeutic Activity of Doxorubicin in HepG2 Cells.
Chemotherapy. 2017;62(2):85-93.