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 Hoechst 33342

  产品编号C1022
  产品包装: 10mg
  产品价格: 202.00元
产品编号 产品名称 产品包装 产品价格
C1022 Hoechst 33342 10mg 202.00元

      Hoechst 33342,也称bisBenzimide H 33342或HOE 33342。分子式为C27H28N6O·3HCl·3H2O,分子量为615.99,
CAS Number 23491-52-3。
      Hoechst 33342是一种可以穿透细胞膜的蓝色荧光染料,对细胞的毒性较低。
      Hoechst 33342染色常用于细胞凋亡检测,染色后用荧光显微镜观察或流式细胞仪检测。Hoechst 33342也常用于普通的细胞核染色,或常规的DNA染色。
      Hoechst 33342的最大激发波长为346nm,最大发射波长为460nm;Hoechst 33342和双链DNA结合后,最大激发波长为350nm,最大发射波长为461nm。
      Hoechst 33342溶于水,溶解度可达20mg/ml。
      用于细胞核染色时,推荐的Hoechst 33342工作浓度为0.5-10μg/ml。
包装清单:

产品编号 产品名称 包装
C1022 Hoechst 33342 10mg
说明书 1份

保存条件:
      -20℃避光保存,一年有效。
注意事项:
      荧光染料都存在淬灭的问题,建议染色后尽量当天完成检测。
      为减缓荧光淬灭可以使用抗荧光淬灭封片液。抗荧光淬灭封片液(P0126)可以向碧云天订购。
      Hoechst 33342对人体有害,请注意适当防护。
      本产品仅限于专业人员的科学研究用,不得用于临床诊断或治疗,不得用于食品或药品,不得存放于普通住宅内。
      为了您的安全和健康,请穿实验服并戴一次性手套操作。

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C1002 DAPI 5mg/ml×0.2ml
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使用本产品的文献:
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Effect of alpha tocopherol acetate in Walker 256/B cells-induced oxidative damage in a rat model of breast cancer skeletal metastases.
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Protective effects of Asiaticoside on acute liver injury induced by lipopolysaccharide/D-galactosamine in mice.
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Pretreatment with the total flavone glycosides of Flos Abelmoschus manihot and hyperosideprevents glomerular podocyte apoptosis in streptozotocin-induced diabetic nephropathy.
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52.Tu Z, Li H, Ma Y, Tang B, Tian J, Akers W, Achilefu S, Gu Y
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53.Zheng X, Tian J, Weng L, Wu L, Jin Q, Zhao J, Wang L.
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Estrogen receptor β potentiates the antiproliferative effect of raloxifene and affects the cellmigration and invasion in HCT-116 colon cancer cells.
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56.Cheng J, Tang W, Su Z, Guo J, Tong L, Wei Q.
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58.Chen LP, Li ZF, Ping M, Li R, Liu J, Xie XH, Song XJ, Guo L.
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Antiproliferative effect of alpinetin in BxPC-3 pancreatic cancer cells.
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63.Yao Q, Zhang AM, Ma H, Lin S, Wang XX, Sun JG, Chen ZT.
Novel molecular beacons to monitor microRNAs in non-small-cell lung cancer.
Mol Cell Probes. 2012 Oct;26(5):182-7. 
64.Zhang B, Wang Y, Pang X.
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65.Xie X, Sun A, Zhu W, Huang Z, Hu X, Jia J, Zou Y, Ge J.
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66.Shen HJ, Shi H, Ma K, Xie M, Tang LL, Shen S, Li B, Wang XS, Jin Y.
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68.Li J, Cheng Y, Zhang X, Zheng L, Han Z, Li P, Xiao Y, Zhang Q, Wang F.
The in vivo immunomodulatory and synergistic anti-tumor activity of thymosin α1-thymopentin fusion peptide and its binding to TLR2.
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69.Zhu W, Shi XL, Xiao JQ, Gu GX, Ding YT, Ma ZL.
Effects of xenogeneic adipose-derived stem cell transplantation on acute-on-chronic liver failure.
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70.Shen H, Shi H, Xie M, Ma K, Li B, Shen S, Wang X, Jin Y.
Biodegradable chitosan/alginate BSA-gel-capsules for pH-controlled loading and release of doxorubicin and treatment of pulmonary melanoma.
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71.Lei W, Liu HB, Wang SB, Zhou XM, Zheng SD, Guo KN, Ma BY, Xia YL, Tan WS, Liu XY, Wang YG.
Tumor suppressor in lung cancer-1 (TSLC1) mediated by dual-regulated oncolytic adenovirus exerts specificantitumor actions in a mouse model.
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Generation of an effective anti-lung cancer vaccine by DTPP-mediated photodynamic therapy and mechanisticstudies.
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73.Han F, Xu Y, Jiang D, Qin Y, Chen H.
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74.Liu Y, He G, Wang Y, Guan X, Pang X, Zhang B.
MCM-2 is a therapeutic target of Trichostatin A in colon cancer cells.
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75.Zhou HL, Zheng YJ, Cheng XZ, Lv YS, Gao R, Mao HP, Chen Q.
Intercellular Transfer of P-Glycoprotein from the Drug Resistant Human Bladder Cancer Cell Line BIU-87 Does NotRequire Cell-to-Cell Contact.
J Urol. 2013 Sep;190(3):1069-75.
76.Zhu K, Guo C, Xia Y, Lai H, Yang W, Wang Y, Song D, Wang C.
Transplantation of novel vascular endothelial growth factor gene delivery system manipulated skeletal myoblastspromote myocardial repair.
Int J Cardiol. 2013 Oct 3;168(3):2622-31.
77.Wang J, Chen Y, Zhang W, Zheng G, Meng S, Che H, Ke T, Yang J, Chen J, Luo W.
Akt Activation Protects Liver Cells from Apoptosis in Rats during Acute Cold Exposure.
Int J Biol Sci. 2013 May 25;9(5):509-17. 
78.Chen Q, Sun J.
Implication of Oxidative Stress in Dose-Dependent Toxicity of Silica Nanoparticles in Hepatocytes .
Advanced Materials Research.2013;647:42-5.
79.Xu C, Liu C, Huang W, Tu S, Wan F.
Effect of Mst1 overexpression on the growth of human hepatocellular carcinoma HepG2 cells and the sensitivityto cisplatin in vitro.
Acta Biochim Biophys Sin (Shanghai).2013 Apr;45(4):268-79. 
80.Yin T, Wang P, Li J, Zheng R, Zheng B, Cheng D, Li R, Lai J, Shuai X.
Ultrasound-sensitive siRNA-loaded nanobubbles formed by hetero-assembly of polymeric micelles andliposomes and their therapeutic effect in gliomas.
Biomaterials. 2013 Jun;34(18):4532-43.  
81.Wang B, Yu T, Dong X, Zhang Z, Song L, Xu Y, Zhang XH.
Edwardsiella tarda invasion of fish cell lines and the activation of divergent cell deappth pathways.
Vet Microbiol. 2013 May 3;163(3-4):282-9. 
81.Wang JJ, Liu YL, Sun YC, Ge W, Wang YY, Dyce PW, Hou R, Shen W.
Basic Fibroblast Growth Factor Stimulates the Proliferation of Bone Marrow Mesenchymal Stem Cells in Giant Panda (Ailuropoda melanoleuca).
PLoS One. 2015 Sep 16;10(9):e0137712.
82.Hou L, Li Y, Song H, Zhang Z, Sun Y, Zhang X, Wu K.
Protective Macroautophagy Is Involved in Vitamin E Succinate Effects on Human Gastric Carcinoma Cell Line SGC-7901 by Inhibiting mTOR Axis Phosphorylation.
PLoS One. 2015 Jul 13;10(7):e0132829.
83.Wu X, Zhao B, Cheng Y, Yang Y, Huang C, Meng X, Wu B, Zhang L, Lv X, Li J.
Melittin induces PTCH1 expression by down-regulating MeCP2 in human hepatocellular carcinoma SMMC-7721 cells.
Toxicol Appl Pharmacol. 2015 Oct 1;288(1):74-83.
84.Gao S, Yu Y, Ma ZY, Sun H, Zhang YL, Wang XT, Wang C, Fan WM, Zheng QY, Ma CL.
NMDAR-Mediated Hippocampal Neuronal Death is Exacerbated by Activities of ASIC1a.
Neurotox Res. 2015 Aug;28(2):122-37.
85.Wang X, Ma Z, Fu Z, Gao S, Yang L, Jin Y, Sun H, Wang C, Fan W, Chen L, Zheng QY, Bi G, Ma CL.
Hydroxysafflor Yellow A Protects Neurons From Excitotoxic Death through Inhibition of NMDARs.
ASN Neuro. 2016 Apr 10;8(2). pii: 1759091416642345.
86.Yang F, Yan G, Li Y, Han Z, Zhang L, Chen S, Feng C, Huang Q, Ding F, Yu Y, Bi C, Cai B, Yang L.
Astragalus Polysaccharide Attenuated Iron Overload-Induced Dysfunction of Mesenchymal Stem Cellsvia Suppressing Mitochondrial ROS.
Cell Physiol Biochem. 2016;39(4):1369-79.
87.Li L, Liu JC, Lai FN, Liu HQ, Zhang XF, Dyce PW, Shen W, Chen H.
Di (2-ethylhexyl) Phthalate Exposure Impairs Growth of Antral Follicle in Mice.
PLoS One. 2016 Feb 4;11(2):e0148350.
88.Wang Y, Qiu Y, Yin S, Zhang L, Shi K, Gao H, Zhang Z, He Q.
A functional nanocarrier that copenetrates extracellular matrix and multiple layers of tumor cells forsequential and deep tumor autophagy inhibitor and chemotherapeutic delivery.
Autophagy. 2016 Dec 2:1-12.
89.Liu Y, Zhi D, Li M, Liu D, Wang X, Wu Z, Zhang Z, Fei D, Li Y, Zhu H, Xie Q, Yang H, Li H.
Shengmai Formula suppressed over-activated Ras/MAPK pathway in C. elegans by openingmitochondrial permeability transition pore via regulating cyclophilin D.
Sci Rep. 2016 Dec 16;6:38934.
90.You F, Li Q, Jin G, Zheng Y, Chen J, Yang H.
Genistein protects against Aβ25-35 induced apoptosis of PC12cells through JNK signaling and modulation of Bcl-2 family messengers.
BMC Neurosci. 2017 Jan 12;18(1):12.
91.Qian L, Li X, Ye P, Wang G, Dai W, Liu Y, Gao Q, Shen G.
Oxymatrine induces apoptosis and inhibits invasion in Gallbladder carcinoma via PTEN/PI3K/AKTpathway.
Cytotechnology. 2017 Nov 23.
92.Shan ZL, Zhong L, Xiao CL, Gan LG, Xu T, Song H, Yang R, Li L, Liu BZ.
Shikonin suppresses proliferation and induces apoptosis in human leukemia NB4 cells through modulation of MAPKs and c Myc.
Mol Med Rep. 2017 Sep;16(3):3055-3060.
93.Yan X, Xun M, Dou X, Wu L, Han Y, Zheng J.
Regulation of Na+-K+-ATPase effected high glucose-induced myocardial cell injury through c-Srcdependent NADPH oxidase/ROS pathway.
Exp Cell Res. 2017 Aug 15;357(2):243-251.
94.Wang Z, Liao K, Zuo W, Liu X, Qiu Z, Gong Z, Liu C, Zeng Q, Qian Y, Jiang L, Bu Y, Hong S, Hu G.
Depletion of NFBD1/MDC1 Induces Apoptosis in Nasopharyngeal Carcinoma Cells Through the p53-ROS-Mitochondrial Pathway.
Oncol Res. 2017 Jan 2;25(1):123-136.
95.Hu Y, Xiong LL, Zhang P, Wang TH.
Microarray expression profiles of genes in lung tissues of rats subjected to focal cerebralischemia-induced lung injury following bone marrow-derived mesenchymal stem cell transplantation.
Int J Mol Med. 2017 Jan;39(1):57-70.
96.Geng YD, Zhang C, Lei JL, Yu P, Xia YZ, Zhang H, Yang L, Kong LY.
Walsuronoid B induces mitochondrial and lysosomal dysfunction leading to apoptotic rather than autophagic cell death via ROS/p53 signaling pathways in liver cancer.
Biochem Pharmacol. 2017 Oct 15;142:71-86.
97.Zhang Y, Wu JY, Weng LH, Li XX, Yu LJ, Xu Y.
Valproic acid protects against MPP+-mediated neurotoxicity in SH-SY5Y Cells through autophagy.
Neurosci Lett. 2017 Jan 18;638:60-68.
98.Fan Y, Liu J, Liu D, Zhou Z, Bao Y, Wang J, Zhao Q, Xu Y.
NSCA-1-a novel N-substituted coumalamide derivative-increases Adriamycin sensitivity in HepG2/adriamycin cells through modulating Akt/GSK-3β signaling and p53-dependant apoptotic pathway.
Environ Toxicol Pharmacol. 2017 Jan;49:1-7.
99.Chen GH, Xu CS, Zhang J, Li Q, Cui HH, Li XD, Chang LP, Tang RJ, Xu JY, Tian XQ, Huang PS, Xu J, Jin C, Yang YJ.
Inhibition of miR-128-3p by Tongxinluo Protects Human Cardiomyocytes from Ischemia/reperfusion Injury via Upregulation of p70s6k1/p-p70s6k1.
Front Pharmacol. 2017 Oct 30;8:775.
100.Hao J, Yang Z, Wang L, Zhang Y, Shu Y, Jiang L, Hu Y, Lv W, Dong P, Liu Y.
Downregulation of BRD4 inhibits gallbladder cancer proliferation and metastasis and inducesapoptosis via PI3K/AKT pathway.
Int J Oncol. 2017 Sep;51(3):823-831.
101.Liu W, Wang X, Liu Z, Wang Y, Yin B, Yu P, Duan X, Liao Z, Chen Y, Liu C, Li X, Dai Y, Tao Z.
SGK1 inhibition induces autophagy-dependent apoptosis via the mTOR-Foxo3a pathway.
Br J Cancer. 2017 Oct 10;117(8):1139-1153.
102.Liu X, Qiu Z, Wang Z, Zuo W, Gong Z, Liu C, Zeng Q, Qian Y, Jiang L, Li Y, Bu Y, Hu G.
NFBD1/MDC1 participates inthe regulation of proliferation and apoptosis in human laryngealsquamous cell carcinoma.
Clin Transl Oncol. 2017 Sep 18.
103.Liu JC, Lai FN, Li L, Sun XF, Cheng SF, Ge W, Wang YF, Li L, Zhang XF, De Felici M, Dyce PW, Shen W.
Di (2-ethylhexyl) phthalate exposure impairs meiotic progression and DNA damage repair in fetalmouse oocytes in vitro.
Cell Death Dis. 2017 Aug 3;8(8):e2966.
104.Ying C, Xiao BD, Qin Y, Wang BR, Liu XY, Wang RW, Fang L, Yan H, Zhou XM, Wang YG.
GOLPH2-regulated oncolytic adenovirus, GD55, exerts strong killing effect on human prostatecancer stem-like cells in vitro and in vivo.
Acta Pharmacol Sin. 2017 Sep 7.
105.Liu XY, Zhang LJ, Chen Z, Liu LB.
The PTEN inhibitor bpV(pic) promotes neuroprotection against amyloid β-peptide(25-35)-inducedoxidative stress and neurotoxicity.
Neurol Res. 2017 Aug;39(8):758-765.
106.Zhai Y1, Li Y2, Wang Y3, Cui J2, Feng K4, Kong X2, Chen L5.
Psoralidin, a prenylated coumestan, as a novel anti-osteoporosis candidate to enhance boneformation of osteoblasts and decrease bone resorption of osteoclasts.
Eur J Pharmacol. 2017 Apr 15;801:62-71.
107.Wang Y1, Qiu Y1, Yin S1, Zhang L1, Shi K1, Gao H1, Zhang Z1, He Q1.
A functional nanocarrier that copenetrates extracellular matrix and multiple layers of tumor cells for sequential and deep tumor autophagy inhibitor and chemotherapeutic delivery.
Autophagy. 2017 Feb;13(2):359-370.
108.Yang LL1, Zhao Y1, Luo SM1, Ma JY1, Ge ZJ1, Shen W1, Yin S2.
Toxic Effects and Possible Mechanisms of HydrogenSulfide and/or Ammonia on Porcine OocyteMaturation in vitro.
Toxicol Lett. 2017 Dec 29. pii: S0378-4274(17)31529-1.
109.Guo Y, Song Z, Zhou M, Yang Y, Zhao Y, Liu B, Zhang X.
Infiltrating macrophages in diabetic nephropathy promote podocytes apoptosis via TNF-α-ROS-p38MAPK pathway.
Oncotarget. 2017 Jun 7;8(32):53276-53287.
110.Sun L, Li Y, Jia X, Wang Q, Li Y, Hu M, Tian L, Yang J, Xing W, Zhang W, Wang J, Xu H, Wang L, Zhang D, Ren H.
Neuroprotection byIFN-γ via astrocyte-secreted IL-6 in acute neuroinflammation.
Oncotarget. 2017 Jun 20;8(25):40065-40078.
111.Zhao C, Yao X, Chen X, Wu W, Xi F, Yang G, Yu T.
Knockdown of ubiquitin D inhibits adipogenesis duringthe differentiation of porcineintramuscular and subcutaneous preadipocytes.
Cell Prolif. 2017 Nov 23.
112.Wu J, Yang X, Lu H, Liu L, Xu B, Zheng S, Yu B, Jie K, Wan F.
Inhibitory effect and mechanism of exogenous mammalian sterile 20-like kinase 1 on the growth of human colorectal cancer.
Oncol Lett. 2017 Apr;13(4):2656-2664.
113.Xiao B, Qin Y, Ying C, Ma B, Wang B, Long F, Wang R, Fang L, Wang Y.
Combination of oncolytic adenovirus and luteolin exerts synergistic antitumor effects in colorectal cancer cells and a mouse model.
Mol Med Rep. 2017 Dec;16(6):9375-9382.
114.Wen Y, He W, Jiang M, Zeng M, Cai L.
Deriving cells expressing markers of female germ cells from premature ovarian failure patient-specific induced pluripotent stem cells.
Regen Med. 2017 Mar;12(2):143-152.
115.Wu X, Gao H, Sun W, Yu J, Hu H, Xu Q, Chen X.
Nepetoidin B,a Natural Product, Inhibits LPS-stimulated Nitric Oxide Production via Modulation of iNOS Mediated by NF-κB/MKP-5 Pathways.
Phytother Res. 2017 Jul;31(7):1072-1077.
116.Xiong LL, Liu F, Lu BT, Zhao WL, Dong XJ, Liu J, Zhang RP, Zhang P, Wang TH.
Bone Marrow Mesenchymal Stem-Cell Transplantation Promotes Functional ImprovementAssociated with CNTF-STAT3 Activation after Hemi-Sectioned Spinal Cord Injury in Tree Shrews.
Front Cell Neurosci. 2017 Jun 28;11:172.
117.Liang J, Wang WF, Xie S, Zhang XL, Qi WF, Zhou XP, Hu JX, Shi Q, Yu RT.
β-transducin repeat-containing E3 ubiquitin protein ligase inhibits migration, invasion and proliferation of glioma cells.
Oncol Lett. 2017 Sep;14(3):3131-3135.
118.Li Y, Sun Y, Cao T, Su Q, Li Z, Huang M, Ouyang R, Chang H, Zhang S, Miao Y.
A cation-exchange controlled core-shell MnS@Bi2S3 theranostic platform for multimodal imaging guided radiation therapy with hyperthermia boost.
Nanoscale. 2017 Oct 5;9(38):14364-14375.
119.Li X, Yan X, Wang Y, Wang J, Zhou F, Wang H, Xie W, Kong H.
NLRP3 inflammasome inhibition attenuates silica-induced epithelial to mesenchymal transition (EMT) in human bronchial epithelial cells.
Exp Cell Res. 2017 Dec 16. pii: S0014-4827(17)30668-7.
120.Xu Z, Zheng M, Zhang L, Zhang X, Zhang Y, Cui X, Gong X, Xi R, Bai R.
Effect of ATP and Bax onthe apoptosis of Eimeria tenella host cells.
BMC Vet Res. 2017 Dec 28;13(1):399.
121.Chang S, Ruan WC, Xu YZ, Wang YJ, Pang J, Zhang LY, Liao H, Pang T.
The natural product 4,10-aromadendranediol induces neuritogenesis in neuronal cells in vitro through activation of the ERK pathway.
Acta Pharmacol Sin. 2017 Jan;38(1):29-40.
122.Sun Y, Wang C, Meng Q, Liu Z, Huo X, Sun P, Sun H, Ma X, Peng J, Liu K.
Targeting P-glycoprotein and SORCIN: Dihydromyricetin strengthens anti-proliferative efficiency of adriamycin via MAPK/ERK and Ca2+-mediated apoptosis pathways in MCF-7/ADR and K562/ADR.
J Cell Physiol. 2018 Apr;233(4):3066-3079.