Natural compounds from plants and animals occupy an important place in the development of new drugs. According to the U.S. Food and Drug Administration (FDA), 34% of small molecule-based drugs were natural compounds or their direct derivatives during 1981-2010, including statins, microtubule protein-binding anticancer drugs, and immunosuppressants [1]。
In particular, medicinal plants have been a valuable source of therapeutic medicines for thousands of years, and many of today's medicines are still plant-derived natural products or their derivatives. A record of the Mesopotamian medical system from 2600 B.C. is the earliest known written record of plant medicinal uses and includes about 1,000 plant-derived medicines; more than 700 medicines, primarily of plant origin, are also recorded in the Egyptian "Ebers Papyrus" from around 1550 B.C.; and traditional Chinese medicine in China has been extensively documented for thousands of years [2]. Nowadays, the identification and screening of active ingredients in traditional Chinese medicine has been an important research direction for many pharmacologists!
Recently, Beyotime has launched nearly 300 HPLC-grade natural compounds mentioned in the Chinese Pharmacopoeia, which are generally considered as the active ingredients of traditional Chinese medicines (TCM), and can be used for the screening of active natural products, basic research on the substance of TCM, and the quality control of TCM.
Figure 1. Chemical structure of Liquiritin
Liquiritin (SM2097), a flavonoid, was first isolated from Glycyrrhiza uralensis by Shinoda and Ueda in 1934. In recent years, pharmacologists have investigated pharmacological effects of Liquiritin, including neuroprotective, cardiovascular protective, pulmonary protective, hepatoprotective, dermatoprotective, antitumor, and intestinal flora regulating effects. Therefore, Liquiritin may be a promising alternative drug for the treatment of neurodegenerative diseases, depression, skin diseases, cardiovascular diseases and even tumors [3].
Product Features
High purity: 98%, HPLC.
Wide range: Including sugars, aldehydes, alcohols, ketones, phenols, esters, alkenes, ethers, sterols, glycosides, saponins, alkaloids, statins, lignin, endogenous chemical components, and other common natural compounds.
Multiple specifications: 10mM x 0.2ml, 5mg, 25mg, 100mg, etc.
Cost-effective: Down to ¥1.7/ml.
Product List
| Cat. No. | Product Name | Compound Type | Signaling Pathway | Pack Size |
| SM1006 | 3,6'-Disinapoylsucrose | phenylpropanoid | Anti-oxidation | 10mM×0.2ml; 5mg; 25mg; 100mg |
| SM1010 | Plantamajoside | phenylpropanoid | Inflammation | 10mM×0.2ml; 5mg; 25mg; 100mg |
| … | ||||
| SM2009 | Safflomin A | flavonoid | Rac1/Akt | 10mM×0.2ml; 5mg; 25mg; 100mg |
| SM2033 | Vitexin | flavonoid | Inflammation | 10mM×0.2ml; 5mg; 25mg; 100mg |
| … | ||||
| SM2231 | 5-O-Methylvisammioside | chromone | iNOS; Inflammation | 10mM×0.2ml; 5mg; 25mg; 100mg |
| SM2235 | Prim-O-glucosylcimifugin | chromone | JAK2/STAT3 | 10mM×0.2ml; 5mg; 25mg; 100mg |
| … | ||||
| SM3037 | Sennoside B | quinone | PDGFR-β | 10mM×0.2ml; 5mg; 25mg; 100mg |
| SM3045 | Mollugin | quinone | NF-kB; p38-Smad | 10mM×0.2ml; 5mg; 25mg; 100mg |
| … | ||||
| SM4016 | Leonurine Hydrochloride | alkaloid | Autophagy; AMPK/SREBP1; PI3K/Akt | 10mM×0.2ml; 5mg; 25mg; 100mg |
| SM4036 | Peiminine | alkaloid | TGF-β; CTGF; ERK1/2; NF-κB; FasL | 10mM×0.2ml; 5mg; 25mg; 100mg |
| … | ||||
| SM5020 | Dehydrocostus Lactone | terpenoid | NF-κB; Apoptosis | 10mM×0.2ml; 5mg; 25mg; 100mg |
| SM5024 | Costunolide | terpenoid | c-Myc/p53; AKT/14-3-3 | 10mM×0.2ml; 5mg; 25mg; 100mg |
| … | ||||
| SM7004 | Tenacissoside H | steroid | PI3K/Akt-NF-κB | 10mM×0.2ml; 5mg; 25mg; 100mg |
| SM7020 | Dioscin | steroid | Apoptosis | 10mM×0.2ml; 5mg; 25mg; 100mg |
| … | ||||
| SM8004 | 10-Gingerol | phenol | Apoptosis | 10mM×0.2ml; 5mg; 25mg; 100mg |
| SM8008 | 6-Gingerol | phenol | Apoptosis; AMPK | 5mg; 25mg; 100mg |
| … | ||||
| SM9028 | Crocin I | pigment | Apoptosis | 10mM×0.2ml; 5mg; 25mg; 100mg |
| SM9032 | Crocin Ⅱ | pigment | - | 10mM×0.2ml; 5mg; 25mg; 100mg |
| … | ||||
| SM9036 | (-)-Fucose | saccharide | - | 10mM×0.2ml; 5mg; 25mg; 100mg |
| SM9040 | Nystose | saccharide | - | 10mM×0.2ml; 5mg; 25mg; 100mg |
| … | ||||
| SM9068 | Ginkgolic Acid (C13:0) | Organic acid | Anticariogenic | 10mM×0.2ml; 5mg; 25mg; 100mg |
| … | ||||
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References:
1. Harvey AL, Edrada-Ebel R, Quinn RJ. The re-emergence of natural products for drug discovery in the genomics era. Nat Rev Drug Discov. 2015;14(2):111-129. doi:10.1038/nrd4510
2.Atanasov AG, Waltenberger B, Pferschy-Wenzig EM, et al. Discovery and resupply of pharmacologically active plant-derived natural products: A review. Biotechnol Adv. 2015;33(8):1582-1614. doi:10.1016/j.biotechadv.2015.08.001
3.Qin J, Chen J, Peng F, et al. Pharmacological activities and pharmacokinetics of liquiritin: A review. J Ethnopharmacol. 2022;293:115257. doi:10.1016/j.jep.2022.115257