中文 | English
订货电话
400-1683301
800-8283301
电话订货时间:
工作日9:00-17:00
订货邮件
order@beyotime.com
订货QQ
4001683301
微信在线咨询
订单下载
碧云天订单.xls
细胞相关> 细胞死亡与自噬> 细胞凋亡
Caspase抑制剂Z-VAD-FMK
产品编号: C1202-0.02ml
产品包装:20mM×0.02ml
价格: ¥ 372.00
产品简介
使用说明
产品文件
相关产品
相关论文
产品问答
产品编号 产品名称 产品包装 产品价格
C1202-0.02ml Caspase抑制剂Z-VAD-FMK 20mM×0.02ml 372.00元
C1202-0.1ml Caspase抑制剂Z-VAD-FMK 20mM×0.1ml 725.00元
C1202-5mg Caspase抑制剂Z-VAD-FMK 5mg 1792.00元

Caspase抑制剂Z-VAD-FMK(Caspase Inhibitor Z-VAD-FMK)是一种可以穿透细胞膜的泛Caspase抑制剂(Cell permeable pan caspase inhibitor),可以抑制由Caspase激活导致的细胞凋亡。
本Caspase抑制剂Z-VAD-FMK是一种不可逆的Caspase广普抑制剂,分子式为Z-Val-Ala-Asp-CH2F,即C21H28FN3O7,分子量为453.5,纯度>95%。
Caspase抑制剂Z-VAD-FMK是一种最常用的细胞凋亡抑制剂,常用于观察特定的细胞凋亡是否通过Caspase激活来介导。
Caspase抑制剂Z-VAD-FMK不仅可以穿透细胞膜抑制细胞内的Caspase,也可以用于抑制体外纯化或粗抽提的Caspase。
本Caspase抑制剂Z-VAD-FMK 20mM包装产品配制在DMSO中,可以直接使用。5mg包装为粉末装。
包装清单:

产品编号 产品名称 包装
C1202-0.02ml Caspase抑制剂Z-VAD-FMK 20mM×0.02ml
C1202-0.1ml Caspase抑制剂Z-VAD-FMK 20mM×0.1ml
C1202-5mg Caspase抑制剂Z-VAD-FMK 5mg
说明书 1份

保存条件:
-20℃保存,一年有效。
注意事项:
如果每次使用量少,使用次数较多,请适当分装。反复冻融会影响本抑制剂的使用效果。
如果希望适当稀释后再分装保存,请使用DMSO进行稀释。
本Caspase抑制剂Z-VAD-FMK在4℃、冰浴等较低温度情况下会凝固而粘在离心管管底、管壁或管盖内,可以20-25℃水浴温育片刻至全部融解后使用。
本产品仅限于专业人员的科学研究用,不得用于临床诊断或治疗,不得用于食品或药品,不得存放于普通住宅内。
为了您的安全和健康,请穿实验服并戴一次性手套操作。 

使用说明:
1. Caspase抑制剂Z-VAD-FMK在终浓度为20μM时可以非常显著地抑制大多数细胞凋亡诱导剂诱导的细胞凋亡。Caspase抑制剂Z-VAD-FMK抑制细胞凋亡的常见有效浓度范围为5-100μM。
2. Caspase抑制剂Z-VAD-FMK用于抑制细胞凋亡时至少需要和细胞凋亡诱导剂同时加入,或者需在细胞凋亡诱导剂加入前10-30分钟加入到细胞培养液中,或参考相关文献进行。
3. 如果用于抑制纯化或粗抽提的Caspase,推荐Caspase抑制剂Z-VAD-FMK与待测样品预孵育10-20分钟,再进行后续测定。
物质安全数据单
输入右侧验证码点击下载:
更换校验码
质检证书
输入批号搜寻COA
搜索
相关产品请点击如下按钮:
使用本产品的文献:
1. Li W, Jiang Z, Li T, Wei X, Zheng Y, Wu D, Yang L, Chen S, Xu B, Zhong M, Jiang J, Hu Y, Su H, Zhang M, Huang X, Geng S, Weng J, Du X, Liu P, Li Y, Liu H, Yao Y, Li P.
.
Mol Cancer. 2015 Feb 3;14:26. (IF 15.302)
2. Hailin Tu, Weihang Xiong, Jie Zhang, Xueqiang Zhao, Xin Lin
.
Nat Commun. 2022 Nov 3;13(1):6603. doi: 10.1038/s41467-022-34080-4. (IF 12.121)
3. Wei Wu, Yang Qu, Shengqing Yu, Sa Wang, Yuncong Yin, Qinfang Liu, Chunchun Meng, Ying Liao, Zaib Ur Rehman, Lei Tan, Cuiping Song, Xusheng Qiu, Weiwei Liu, Chan Ding, Yingjie Sun
.
mBio. 2021 Jun 29;12(3):e0100521. doi: 10.1128/mBio.01005-21. (IF 6.784)
4. Teng Y, Gao M, Wang J, Kong Q, Hua H, Luo T, Jiang Y.
.
Cell Death Dis. 2014 Feb 13;5:e1060. (IF 6.304)
5. Song ZH, Yu HY, Wang P, Mao GK, Liu WX, Li MN, Wang HN, Shang YL, Liu C, Xu ZL, Sun QY, Li W.
.
Cell Death Dis. 2015 Jan 15;6:e1589. (IF 6.304)
6. Liu SY, Song JY, Fan B, Wang Y, Pan YR, Che L, Sun YJ, Li GY
.
FREE RADICAL BIO MED. 2018 Dec;129:569-581. (IF 6.17)
7. Zhu L, Yuan H, Guo C, Lu Y, Deng S, Yang Y, Wei Q, Wen L, He Z.
.
J Cell Physiol. 2012 May;227(5):1814-20. (IF 5.546)
8. Zhao H, Xu X, Lei S, Shao D, Jiang C, Shi J, Zhang Y, Liu L, Lei S, Sun H, Huang Q
.
J Cell Physiol. 2019 May 234(5):6414-6427. (IF 5.546)
9. Liang Zhou, Wenjun Yu, David S Jayabalan, Ruben Niesvizky, Samie R Jaffrey, Xiangao Huang, Guoqiang Xu
.
Front Cell Dev Biol. 2020 Dec 17;8:605989. doi: 10.3389/fcell.2020.605989. (IF 5.201)
10. Song P, Ye L, Fan J, Li Y, Zeng X, Wang Z, Wang S, Zhang G, Yang P, Cao Z, Ju D.
.
ONCOTARGET. 2015 Feb 28;6(6):3861-73. (IF 5.168)
11. Ma LS, Jiang CY, Cui M, Lu R, Liu SS, Zheng BB, Li L, Li X.
.
Acta Pharmacol Sin. 2013 Aug;34(8):1093-100. (IF 5.064)
16. PengYB, ZhouP, Chu C, Liu EH, et al
.
Chinese Journal of Natural Medicines. ,2011 Jul, 9(4),305-316 (IF 1.773)
17. Zhang Y, Zeng F, Liu X, Li Y, Zhou J, Huang Y, Wang Y, Zhou S, Zhu W, Shu E, Zhou G, Chen G
.
Xenobiotica. 2011 Jul;41(7):593-602. (IF 1.902)
18. Sun X, Huo X, Luo T, Li M, Yin Y, Jiang Y.
.
J Cell Mol Med. 2011 Nov;15(11):2389-98 (IF 4.486)
19. Khan M, Zheng B, Yi F, Rasul A, Gu Z, Li T, Gao H, Qazi JI, Yang H, Ma T
.
EVID-BASED COMPL ALT. 2012;2012:957568. (IF 1.813)
21. Mao ZG, Zhou J, Wang H, He DS, Xiao WW, Liao GZ, Qiu LB, Zhu YH, Wang HJ.
.
Mol Biol Rep. 2012 May;39(5):6227-34. (IF 1.402)
22. Zhao WH, Gou BD, Zhang TL, Wang K.
.
J Cell Biochem. 2012 May;113(5):1776-86. (IF 4.237)
23. Song J, Shu L, Zhang Z, Tan X, Sun E, Jin X, Chen Y, Jia X.
.
CHEM-BIOL INTERACT. 2012 Jun 9;199(1):9-17. (IF 3.723)
24. Tang W, Zhang Y, Qian C, Yuan Z, Du J.
.
INVEST OPHTH VIS SCI. 2012 Jul 24;53(8):4874-80. (IF 3.47)
25. Wang C, Zhang J, Wang Z, Razzaq M, Khan M.
.
AFR J PHARM PHARMACO. 2012 Jul;6(25):1874-82. (IF 0.5)
26. Wang D, Fang L, Li K, Zhong H, Fan J, Ouyang C, Zhang H, Duan E, Luo R, Zhang Z, Liu X, Chen H, Xiao S
.
J Virol. 2012 Sep;86(17):9311-22. (IF 4.501)
27. Wang YQ, Wang L, Zhang MY, Wang T, Bao HJ, Liu WL, Dai DK, Zhang L, Chang P, Dong WW, Chen XP, Tao LY.
.
Neurochem Res. 2012 Sep;37(9):1849-58. (IF 3.038)
28. Chen FH, Lu N, Zhang HW, Zhao L, He LC, Sun HP, You QD, Li ZY, Guo QL.
.
Mol Pharmacol. 2012 Nov;82(5):958-71. (IF 3.664)
29. Wang Y, Zhu X, Yang Z, Zhao X.
.
BIOCHEM BIOPH RES CO. n. 2013 Jan 18;430(3):876-82. (IF 2.985)
30. Song XJ, Xia Y, Wang NY, Zhang LD, Shi XH, Xu YZ, Ye TH, Shi YJ, Zhu YX, Yu LT.
.
PLoS One. 2013 May 30;8(5):e63900. (IF 2.74)
31. Sun B, Cai Y, Li Y, Li J, Liu K, Li Y, Yang Y.
.
Virology. 2013 May 25;440(1):75-83. (IF 2.819)
32. Li Y, Zhu H, Zeng X, Fan J, Qian X, Wang S, Wang Z, Sun Y, Wang X, Wang W, Ju D.
.
Mol Neurobiol. 2013 Jun;47(3):1000-10. (IF 4.5)
33. Deng Q, Zhang Z, Feng X, Li T, Liu N, Lai J, Shuai L, Xiong Q, Fu C, Zou H, Wang Y, Li X, Ma K, Bie P.
.
Gene Ther. 2014 Mar;21(3):317-27. (IF 4.128)
34. Yu X, Wang H, Liu L.
.
APPL MICROBIOL BIOT. 2014 Apr;98(7):3099-110. (IF 3.53)
35. Yang X, Ouyang H, Chen F, Pang D, Dong M, Yang S, Liu X, Peng Z, Wang F, Zhang X, Ren L.
.
J Gen Virol. 2014 Jun;95(Pt 6):1330-7. (IF 3.376)
36. Gao X, Zhang H, Zhuang W, Yuan G, Sun T, Jiang X, Zhou Z, Yuan H, Zhang Z, Dong H.
.
SCI REP-UK. 2014 Jul 11;4:5637. (IF 3.998)
37. Li R, Zhang L, Zhang L, Chen D, Tian J, Cao L, Zhang L.
.
Int Urol Nephrol. 2014 Jul;46(7):1335-44. (IF 1.843)
38. Pan Q, Huang Y, Chen L, Gu J, Zhou X.
.
Hum Cell. 2014 Oct;27(4):162-71. (IF 3.463)
39. Di W, Khan M, Rasul A, Sun M, Sui Y, Zhong L, Yang L, Zhu Q, Feng L, Ma T.
.
Oncol Rep. 2014 Oct;32(4):1585-93. (IF 3.417)
40. Sun M, Zhang N, Wang X, Cai C, Cun J, Li Y, Lv S, Yang Q.
.
TUMOR BIOL . 2014 Oct;35(10):10201-12. (IF 3.65)
41. Zhang Y, Ren X, Shi M, Jiang Z, Wang H, Su Q, Liu Q, Li G, Jiang G.
.
Oncol Rep. 2014 Nov;32(5):2038-46. (IF 3.417)
42. Liu Y, He X, Sui Y, Yu R, Xu G.
.
FEBS Lett. 2015 Aug 4;589(17):2233-40. (IF 3.057)
43. Zhou GZ, Yi YJ, Chen ZY, Zhang QY.
.
Vet Pathol. 2015 Nov;52(6):1258-62. (IF 2.01)
44. Zhao LL, Liu YF, Peng LJ, Fei AM, Cui W, Miao SC, Hermine O, Gressin R, Khochbin S, Chen SJ, Wang J, Mi JQ.
.
CANCER MED-US. 2015 Nov;4(11):1754-66. (IF 3.491)
45. Shi M, Ren X, Wang X, Wang H, Liu G, Yuan X, Zheng S, Yu L, Pan S, Song G, Guo Q, Li L, Zhang X, Zhang Z, Ding H, Jiang G .
.
Int J Oncol. 2016 Feb;48(2):734-46. (IF 3.899)
46. Li K, Yang W, Li Z, Jia W, Li J, Zhang P, Xiao T .
.
Int Immunopharmacol. 2016 May;34:189-98. (IF 3.943)
47. Li K, Zhou R, Wang Jia W, Li Z, Li J, Zhang P, Xiao T .
.
J Ethnopharmacol. 2016 Jun 20;186:351-61. (IF 3.69)
48. He XY, Yuan LY, Li YT, Li M, Chen Y, Yuan H, Wu J, Guo CZ, Li J .
.
Biomed Environ Sci. 2016 Jul;29(7):529-33. (IF 2.656)
49. Zhang X, Shang W, Yuan J, Hu Z, Peng H, Zhu J, Hu Q, Yang Y, Liu H, Jiang B, Wang Y, Li S, Hu X, Rao X .
.
FRONT CELL INFECT MI. 2016 Sep 21;6:109. (IF 4.123)
50. Xing F, Zhan Q, He Y, Cui J, He S, Wang G .
.
PLoS One. 2016 Sep 30;11(9):e0163935. (IF 2.74)
51. Han YY, Tang JJ, Gao RF, Guo X, Lei M, Gao JM .
.
Toxicol In Vitro. 2016 Sep;35:112-20. (IF 2.959)
52. Liu X, Ding S, Shi P, Dietrich R, Märtlbauer E, Zhu K .
.
Cell Microbiol. 2016 Oct 20. doi: 10.1111/cmi.12684. [Epub ahead of print] (IF 3.43)
53. Ruan J, Gao S, Yang J, Li H, Huang H, Zheng X
.
LEUKEMIA LYMPHOMA. 2018 Jan;59(1):162-170. (IF 2.969)
54. Wang Q, Guo Y, Jiang S, Dong M, Kuerban K, Li J, Feng M, Chen Y, Ye L
.
Phytomedicine. 2018 Jan 15;39:160-167. (IF 4.268)
55. Guo CL, Wang LJ, Zhao Y, Liu H, Li XQ, Jiang B, Luo J, Guo SJ, Wu N, Shi DY
.
Mar Drugs. 2018 Jan 25;16(2). pii: E43. (IF 4.073)
56. Hu C, Chen X, Huang Y, Chen Y
.
Apoptosis. 2018 Feb;23(2):132-142. (IF 4.543)
58. Zhang Y, Song J, Zhang W, Liang R, Ma Y, Zhang L, Wei X, Ni J, Wang R.
.
Chem Biol Drug Des. 2018 Aug;92(2):1567-1575. (IF 2.548)
59. Hu C, Chen X, Huang Y, Chen Y
.
Chem Biol Drug Des. 2018 Aug;92(2):1567-1575. (IF 2.548)
60. Shen J, Wang X, Zhou D, Li T, Tang L, Gong T, Su J, Liang P
.
J Cell Mol Med. 2018 Sep;22(9):4221-4235. (IF 4.486)
61. Wen P, Hu TG, Li L, Zong MH, Wu H
.
Food Funct. 2018 Nov 14;9(11):5999-6009. (IF 4.171)
62. Wang J, Qi H, Zhang X, Si W, Xu F, Hou T, Zhou H, Wang A, Li G, Liu Y, Fang Y, Piao HL, Liang X
.
Biomed Pharmacother. 2018 Dec;108:724-733. (IF 4.545)
64. Yang H, Wang C, Zhang L, Lv J, Ni H
.
CHEM-BIOL INTERACT. 2019 Jan 5 297:44-49. (IF 3.723)
66. Zhao L, Zhuang J, Wang Y, Zhou D, Zhao D, Zhu S, Pu J, Zhang H, Yin M, Zhao W, Wang Z, Hong J
.
Front Pharmacol. 2019 Feb 12 10:61. (IF 4.225)
67. Zhao H, Zhao X, Lei S, Zhang Y, Shao D, Jiang C, Sun H, Shi J
.
Food Funct. 2019 Mar 20 10(3):1478-1489. (IF 4.171)
68. Zhai N, Liu K, Li H, Liu Z, Wang H, Korolchuk VI, Carroll B, Pan C, Gan F, Huang K, Chen X
.
Vet Res. 2019 Mar 5 50(1):19. (IF 3.357)
69. Wen W, Yin M, Zhang H, Liu T, Chen H, Qian P, Hu J, Li X
.
Virology. 2019 Sep 535:122-129. (IF 2.819)
70. Ke W, Fang L, Tao R, Li Y, Jing H, Wang D, Xiao S
.
J Virol. 2019 Sep 30 93(20). pii: e00767-19. (IF 4.501)
71. Zhou B, Chen E, Chen J, Zhang J, Zhang N, Chen Z
.
INT J CLIN EXP PATHO. 2019 Oct 1 12(10):3719-3727. eCollection 2019. (IF 0.252)
72. Ting Jiang, Hui Cheng, Jingjing Su, Xuncui Wang, Qiaoxue Wang, Jun Chu, Qinglin Li
.
Toxicol In Vitro. 2020 Feb;62:104715. doi: 10.1016/j.tiv.2019.104715. (IF 2.959)
73. Wei Liu, Yi Chai, Libo Hu, Junhua Wang, Xin Pan, Hongyu Yuan, Zitong Zhao, Yongmei Song, Yuqi Zhang
.
ONCOTARGETS THER. 2020 Mar 13;13:2275-2288. doi: 10.2147/OTT.S243953. (IF 3.337)
74. Jia -Lu Zheng, Shuang-Shuang Wang, Ke-Ping Shen, Xiao-Wei Huang, Miao Li, Lei Chen, Xiao Peng, Hong-Mei An, Bing Hu
.
Pharmazie. 2020 Jun 1;75(6):246-249. doi: 10.1691/ph.2020.0417. (IF 1.198)
75. Shanshan Zhu, Jing Zhou, Xiaoyu Sun, Zhonglou Zhou, Qiqi Zhu
.
J BIOCHEM MOL TOXIC. 2020 Aug;34(8):e22505. doi: 10.1002/jbt.22505. (IF 3.606)
76. Quan-You Zheng, Shen-Ju Liang, Feng Xu, Yi Yang, Jian-Li Feng, Fen Shen, Yu Zhong, Shun Wu, Yong Shu, Dao-Dong Sun, Gui-Lian Xu
.
Int Immunopharmacol. 2020 Aug;85:106692. doi: 10.1016/j.intimp.2020.106692. (IF 3.943)
77. Hui-Fang Deng, Lan-Xin Yue, Ning-Ning Wang, Yong-Qiang Zhou, Wei Zhou, Xian Liu, Yu-Hao Ni, Cong-Shu Huang, Li-Zhen Qiu, Hong Liu, Hong-Ling Tan, Xiang-Lin Tang, Yu-Guang Wang, Zeng-Chun Ma, Yue Gao
.
Front Pharmacol. 2021 Jan 21;11:624529. doi: 10.3389/fphar.2020.624529. (IF 4.225)
78. Xiaochen Wu, Qiqi Li, Fan Zhang, Lijun Wang, Jun Wang, Junting Fan, Guohu Di, Chuanlong Guo
.
Food Chem Toxicol. 2021 Jan;147:111892. doi: 10.1016/j.fct.2020.111892. (IF 4.679)
79. Chaotao Zhang, Cancan Huang, Panpan Yang, Congshan Li, Minqi Li
.
Cell Signal. 2021 Feb;78:109841. doi: 10.1016/j.cellsig.2020.109841. (IF 3.968)
80. Yuchen Xia, Guihua Wang, Manli Jiang, Xueting Liu, Yan Zhao, Yinghui Song, Binyuan Jiang, Demao Zhu, Ling Hu, Zhao Zhang, Ting Cao, Ji Ming Wang, Jinyue Hu
.
Onco Targets Ther. 2021 Jul 5;14:4047-4060. doi: 10.2147/OTT.S313507.
81. Shuxian Yang, Haiyan Xiao, Yunfang Sun, Li Cao
.
Phytother Res. 2021 Oct;35(10):5899-5918. doi: 10.1002/ptr.7299. (IF 4.087)
82. Chen Wang, Ting Ling, Ni Zhong, Liang-Guo Xu
.
Front Microbiol. 2021 Nov 22;12:770600. doi: 10.3389/fmicb.2021.770600. (IF 4.235)
83. Xiangrong Li, Ruixian Ma, Bei Wu, Yuhui Niu, Hongshan Li, Dianyu Li, Jingying Xie, Adi Idris, Ruofei Feng
.
Front Microbiol. 2021 Nov 26;12:788870. doi: 10.3389/fmicb.2021.788870. (IF 4.235)
84. Ruihua Jing, Conghui Hu, Tiantian Qi, Jiaqi Yue, Guangyan Wang, Ming Zhang, Chan Wen, Cheng Pei, Bo Ma
.
Life Sci. 2021 Dec 1;286:120061. doi: 10.1016/j.lfs.2021.120061. (IF 3.647)
85. Guoxing Ou, Xianyu Jiang, Ang Gao, Xiaolong Li, Zijun Lin, Shimin Pei
.
Front Vet Sci. 2022 Feb 4;8:801407. doi: 10.3389/fvets.2021.801407. (IF 2.245)
购物车
会员
顶部